Tbio SCOC Short coiled-coil protein

Protein Summary

Description

Positive regulator of amino acid starvation-induced autophagy. This gene encodes a short coiled-coiled domain-containing protein that localizes to the Golgi apparatus. The encoded protein interacts with ADP-ribosylation factor-like proteins. Pseudogenes of this gene are found on chromosomes 1 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Uniprot Accession IDs

• Q9UIL1
• B7WPH7
• D3DNY7
• E9PB65
• Q6P5T9
• Q7L2Y0
• Q7Z4P2
• Q96JY9
• Q9BZB2

Gene Name

• SCOC

Ensembl ID

• ENST00000338517
• ENSP00000345262
• ENSG00000153130
• ENST00000394203
• ENSP00000377753
• ENST00000394205
• ENSP00000377755
• ENST00000506597
• ENSP00000426649
• ENST00000608372
• ENSP00000477352
• ENST00000614192
• ENSP00000477812

Symbol

• SCOCO
• SCOCO
• UNC-69
• HRIHFB2072

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
transcription factor	0.75
transcription factor perturbation	0.68
disease perturbation	0.62
tissue sample	0.62
cellular component	0.59

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.13   (req: < 5)

Gene RIFs: 6   (req: <= 3)

Antibodies: 72   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 28.13   (req: >= 5)

Gene RIFs: 6   (req: > 3)

Antibodies: 72   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0