SCLY
Selenocysteine lyase
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
histone modification site profile | 0.91 | ||
protein domain | 0.73 | ||
transcription factor binding site profile | 0.66 | ||
tissue sample | 0.65 | ||
virus perturbation | 0.55 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Metabolism | ||||
Reactome | Metabolism of amino acids and derivatives | ||||
Reactome | Metabolism of ingested SeMet, Sec, MeSec into H2Se | ||||
Reactome | Selenoamino acid metabolism | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Metabolism | ||||
Metabolism of amino acids and derivatives | ||||
Metabolism of ingested SeMet, Sec, MeSec into H2Se | ||||
Selenoamino acid metabolism | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Traceable Author Statement (TAS) | Reactome | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 2 | 1 | 2 | 81.5 | |||||
red blood cell distribution width | 3 | 2 | 3 | 79.2 | |||||
hemoglobin measurement | 2 | 1 | 2 | 70.8 | |||||
mathematical ability | 3 | 2 | 3 | 68.4 | |||||
transferrin saturation measurement | 1 | 1 | 1 | 55.2 | |||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
mean corpuscular hemoglobin concentration | 2 | 81.5 | |||||
red blood cell distribution width | 3 | 79.2 | |||||
hemoglobin measurement | 2 | 70.8 | |||||
mathematical ability | 3 | 68.4 | |||||
transferrin saturation measurement | 1 | 55.2 | |||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | selenocysteine lyase | VGNC:14172 | 460055 | |||||
Macaque | selenocysteine lyase | 695511 | ||||||
Mouse | MGI:1355310 | 50880 | ||||||
Rat | RGD:1359514 | 363285 | ||||||
Dog | selenocysteine lyase | 477422 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | selenocysteine lyase | |||||
Macaque | selenocysteine lyase | |||||
Mouse | ||||||
Rat | ||||||
Dog | selenocysteine lyase | |||||
PMID | Year | Title |
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