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Tbio
SCGB2A1
Mammaglobin-B

Protein Summary
Description
May bind androgens and other steroids, may also bind estramustine, a chemotherapeutic agent used for prostate cancer. May be under transcriptional regulation of steroid hormones.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000244930
  • ENSP00000244930
  • ENSG00000124939

Symbol
  • LIPHC
  • MGB2
  • UGB3
  • LPHC
  • LPNC
  • MGB2
  • UGB3
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.56
small molecule perturbation
0.54
disease
0.48
chemical
0.44
biological term
0.42


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 57.03   (req: < 5)
Gene RIFs: 17   (req: <= 3)
Antibodies: 170   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 57.03   (req: >= 5)
Gene RIFs: 17   (req: > 3)
Antibodies: 170   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (99)
DDX31
Tbio
Family:  Enzyme
Novelty:  2.84646195
p_int:  0.999999115
p_ni:  8.76e-7
p_wrong:  9e-9
Data Source:  BioPlex
PCYOX1L
Tdark
Family:  Enzyme
Novelty:  1.25398886
p_int:  0.999997965
p_ni:  0.000002035
Data Source:  BioPlex
HBM
Tdark
Novelty:  0.02658671
p_int:  0.999995207
p_ni:  0.000004791
p_wrong:  2e-9
Score:  0.179
Data Source:  BioPlex,STRINGDB
PLA2G15
Tbio
Family:  Enzyme
Novelty:  0.01546393
p_int:  0.999989839
p_ni:  0.00000301
p_wrong:  0.000007151
Data Source:  BioPlex
GLB1L
Tdark
Family:  Enzyme
Novelty:  0.43027328
p_int:  0.999975952
p_ni:  0.00002404
p_wrong:  8e-9
Data Source:  BioPlex
CCDC148
Tdark
Novelty:  2.81805259
p_int:  0.999946192
p_ni:  0.000050606
p_wrong:  0.000003202
Score:  0.234
Data Source:  BioPlex,STRINGDB
SLC27A2
Tbio
Family:  Transporter
Novelty:  0.01436035
p_int:  0.999926282
p_ni:  0.000073718
Data Source:  BioPlex
LARGE1
Tbio
Family:  Enzyme
Novelty:  0.02518701
p_int:  0.999581079
p_ni:  0.000418916
p_wrong:  6e-9
Data Source:  BioPlex
DAAM2
Tbio
Novelty:  0.07318127
p_int:  0.999404734
p_ni:  0.000595259
p_wrong:  7e-9
Score:  0.187
Data Source:  BioPlex,STRINGDB
EXT1
Tbio
Family:  Enzyme
Novelty:  0.00355951
p_int:  0.999201732
p_ni:  0.000798268
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
2
1
1.1
54.2
sex hormone-binding globulin measurement
2
1
2
35
1
1
1
33.1
1
1
1
33.1
gamma-linolenic acid measurement
1
1
1
6.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1.1
54.2
sex hormone-binding globulin measurement
2
35
1
33.1
1
33.1
gamma-linolenic acid measurement
1
6.2
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
secretoglobin family 2A member 1
VGNC:6541
451249
Mouse
MGI:3780828
102639117
Rat
RGD:735031
361725
Dog
mammaglobin-A
612244
Horse
mammaglobin-B-like
100629936
Species
Name
OMA
EggNOG
Inparanoid
Chimp
secretoglobin family 2A member 1
Mouse
Rat
Dog
mammaglobin-A
Horse
mammaglobin-B-like
Publication Statistics
PubMed Score 57.03
PubMed score by year
PubTator Score 208.51
PubTator score by year
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Related Publications
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PMID
Year
Title