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Tdark
SCGB1D4
Secretoglobin family 1D member 4

Protein Summary
Description
Seems to be involved in the regulation of chemotactic cell migration and invasion.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000358585
  • ENSP00000351395
  • ENSG00000197745

Symbol
  • IIS
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
tissue sample
0.4
tissue
0.38
biological term
0.33
cell line
0.3
cellular component
0.3


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 120.81   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 0   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 120.81   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 0   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (61)
PRUNE1
Tchem
Novelty:  0.02136836
p_int:  0.999998415
p_ni:  0.000001585
Data Source:  BioPlex
NAALAD2
Tchem
Family:  Enzyme
Novelty:  0.18444329
p_int:  0.999885058
p_ni:  0.000052471
p_wrong:  0.000062471
Data Source:  BioPlex
CNTNAP3
Tbio
Novelty:  0.22791524
p_int:  0.999705931
p_ni:  0.000294069
Data Source:  BioPlex
CACNA2D1
Tclin
Family:  IC
Novelty:  0.01744541
p_int:  0.999539044
p_ni:  0.000460956
Data Source:  BioPlex
ADAM9
Tchem
Family:  Enzyme
Novelty:  0.00616626
p_int:  0.999159896
p_ni:  0.000840104
Data Source:  BioPlex
ADGRV1
Tbio
Family:  GPCR
Novelty:  0.01398129
p_int:  0.998200258
p_ni:  0.001799742
Data Source:  BioPlex
BACE1
Tchem
Family:  Enzyme
Novelty:  0.00042175
p_int:  0.996425702
p_ni:  0.001137923
p_wrong:  0.002436375
Score:  0.369
Data Source:  BioPlex,STRINGDB
CACNA2D2
Tclin
Family:  IC
Novelty:  0.02041017
p_int:  0.995998582
p_ni:  0.004001418
Data Source:  BioPlex
CNNM1
Tdark
Novelty:  0.11053515
p_int:  0.991840949
p_ni:  0.008158952
p_wrong:  9.9e-8
Data Source:  BioPlex
LNPEP
Tchem
Family:  Enzyme
Novelty:  0.00249049
p_int:  0.988581365
p_ni:  0.011418635
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
2
2
2
59.5
waist-hip ratio
1
2
2
31.3
heel bone mineral density
1
1
1
6.6
gamma-linolenic acid measurement
1
1
1
6.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist-hip ratio
2
59.5
waist-hip ratio
2
31.3
heel bone mineral density
1
6.6
gamma-linolenic acid measurement
1
6.2
IDG Resources
No IDG generated resources found
Orthologs (2)
1 – 2 of 2
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Dog
secretoglobin family 1D member 2-like
100687441
Pig
secretoglobin family 1D member 1
449006
Species
Name
OMA
EggNOG
Inparanoid
Dog
secretoglobin family 1D member 2-like
Pig
secretoglobin family 1D member 1
Publication Statistics
PubMed Score 120.81
PubMed score by year
PubTator Score 7.10
PubTator score by year
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Related Publications
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PMID
Year
Title