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Tbio
SCFD1
Sec1 family domain-containing protein 1

Protein Summary
Description
Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000396629
  • ENSP00000379870
  • ENSG00000092108
  • ENST00000458591
  • ENSP00000390783
  • ENST00000544052
  • ENSP00000443010

Symbol
  • C14orf163
  • KIAA0917
  • STXBP1L2
  • SLY1
  • RA410
  • SLY1P
  • STXBP1L2
  • C14orf163
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
interacting protein
0.86
trait
0.86
histone modification site profile
0.81
virus perturbation
0.79
disease perturbation
0.74


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.17   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 292   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.17   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 292   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 15
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0