Tbio SCAND1 SCAN domain-containing protein 1

Protein Summary

Description

May regulate transcriptional activity. This gene encodes a SCAN box domain-containing protein. The SCAN domain is a highly conserved, leucine-rich motif of approximately 60 aa originally found within a subfamily of zinc finger proteins. This gene belongs to a family of genes that encode an isolated SCAN domain, but no zinc finger motif. This protein binds to and may regulate the function of the transcription factor myeloid zinc finger 1B. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jan 2011]

Uniprot Accession IDs

• P57086
• Q6IAG7

Gene Name

• SCAND1

Ensembl ID

• ENST00000305978
• ENSP00000301995
• ENSG00000171222
• ENST00000373991
• ENSP00000363103
• ENST00000615116
• ENSP00000481289

Symbol

• SDP1
• RAZ1
• SDP1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
kinase perturbation	0.88
transcription factor binding site profile	0.83
cell type or tissue	0.74
transcription factor perturbation	0.68
transcription factor	0.65

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.87   (req: < 5)

Gene RIFs: 3   (req: <= 3)

Antibodies: 200   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 19.87   (req: >= 5)

Gene RIFs: 3   (req: > 3)

Antibodies: 200   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0