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Tbio
SCAF4
Splicing factor, arginine/serine-rich 15

Protein Summary
Description
May act to physically and functionally link transcription and pre-mRNA processing. This gene likely encodes a member of the arginine/serine-rich splicing factor family. A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre-mRNA splicing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000286835
  • ENSP00000286835
  • ENSG00000156304
  • ENST00000399804
  • ENSP00000382703
  • ENST00000434667
  • ENSP00000402377

Symbol
  • KIAA1172
  • SFRS15
  • SRA4
  • SFRS15
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein complex
0.93
virus perturbation
0.85
transcription factor binding site profile
0.81
histone modification site profile
0.74
protein domain
0.73


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.82   (req: < 5)
Gene RIFs: 8   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 17.82   (req: >= 5)
Gene RIFs: 8   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0