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Tdark
SCAF11
Protein SCAF11

Protein Summary
Description
Plays a role in pre-mRNA alternative splicing by regulating spliceosome assembly.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000369367
  • ENSP00000358374
  • ENSG00000139218
  • ENST00000465950
  • ENSP00000449812

Symbol
  • CASP11
  • SFRS2IP
  • SIP1
  • SRSF2IP
  • SIP1
  • CASP11
  • SFRS2IP
  • SRRP129
  • SRSF2IP
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor binding site profile
0.98
transcription factor perturbation
0.98
kinase perturbation
0.97
ligand (protein) perturbation
0.83
histone modification site profile
0.77


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 167.69   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 39   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 167.69   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 39   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0