You are using an outdated browser. Please upgrade your browser to improve your experience.

Tchem
SBK3
Uncharacterized serine/threonine-protein kinase SBK3

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000612221
  • ENSP00000483467
  • ENSG00000231274

Symbol
  • SGK110
  • SGK110
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
molecular function
0.9
tissue
0.69
protein domain
0.58
cell line
0.43
PubMedID
0.38


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.66   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 18   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.66   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 18   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 1
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (6)
Dark Kinase Knowledgebase
Thumbnail image for Dark Kinase Knowledgebase
The Dark Kinase Knowledgebase is an an online compendium of knowledge and experimental results of understudied kinases.
ProKinO
Thumbnail image for ProKinO
The ProKinO is a protein kinase-specific ontology, which provides a controlled vocabulary of terms, their hierarchy, and relationships unifying sequence, structure, function, mutation and pathway information on kinases.
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Protein-Protein Interactions (7)
FAM86B1
Tdark
Family:  Enzyme
Novelty:  1.47930034
Score:  0.539
Data Source:  STRINGDB
TBCK
Tbio
Family:  Kinase
Novelty:  0.08568145
Score:  0.511
Data Source:  STRINGDB
POMK
Tbio
Family:  Kinase
Novelty:  0.09340344
Score:  0.489
Data Source:  STRINGDB
DNPEP
Tchem
Family:  Enzyme
Novelty:  0.02415651
Score:  0.473
Data Source:  STRINGDB
TEX14
Tbio
Family:  Kinase
Novelty:  0.08515917
Score:  0.473
Data Source:  STRINGDB
PKDCC
Tbio
Family:  Kinase
Novelty:  0.02347112
Score:  0.448
Data Source:  STRINGDB
TM6SF1
Tdark
Novelty:  0.40815928
Score:  0.439
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
3
1
3
85.1
triglyceride measurement
4
3
4
83
insomnia measurement
1
2
0
1.1
45.7
birth weight
1
1
1
43.1
BMI-adjusted waist-hip ratio
3
1
3
38.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
appendicular lean mass
3
85.1
triglyceride measurement
4
83
insomnia measurement
0
1.1
45.7
birth weight
1
43.1
BMI-adjusted waist-hip ratio
3
38.6
Publication Statistics
PubMed Score 0.66
PubMed score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title