Tbio SAT2 Diamine acetyltransferase 2

Protein Summary

Description

Enzyme which catalyzes the acetylation of polyamines. Substrate specificity: norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine.

Uniprot Accession IDs

• Q96F10

Gene Name

• SAT2

Ensembl ID

• ENST00000269298
• ENSP00000269298
• ENSG00000141504

Symbol

• SSAT2
• SSAT2

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
tissue sample	0.72
kinase perturbation	0.71
histone modification site profile	0.66
virus perturbation	0.64
cell type or tissue	0.51

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14   (req: < 5)

Gene RIFs: 7   (req: <= 3)

Antibodies: 123   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 14   (req: >= 5)

Gene RIFs: 7   (req: > 3)

Antibodies: 123   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0