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Tbio
SAMD12
Sterile alpha motif domain-containing protein 12

Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.25   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 62   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 21.25   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (31)
LRRC9
Tdark
Novelty:  0.59020229
Score:  0.78
Data Source:  STRINGDB
SNX25
Tbio
Novelty:  0.15818269
Score:  0.679
Data Source:  STRINGDB
POF1B
Tbio
Novelty:  0.1232792
Score:  0.596
Data Source:  STRINGDB
FAM9C
Tdark
Novelty:  0.86727989
Score:  0.539
Data Source:  STRINGDB
BTG1
Tbio
Novelty:  0.10129789
Score:  0.538
Data Source:  STRINGDB
BANF2
Tdark
Novelty:  0.13092902
Score:  0.538
Data Source:  STRINGDB
AARD
Tdark
Novelty:  0.14606491
Score:  0.526
Data Source:  STRINGDB
ARL15
Tbio
Family:  Enzyme
Novelty:  0.09327102
Score:  0.524
Data Source:  STRINGDB
UTP23
Tbio
Novelty:  0.19155319
Score:  0.511
Data Source:  STRINGDB
NDUFAF8
Tbio
Novelty:  1.48457646
Score:  0.511
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (12)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil count
5
4
5
90.4
educational attainment
1
8
8
84.9
osteoprotegerin measurement
1
1
1
73.8
brain measurement
1
1
0
9.9
66
cortical surface area measurement
1
1
0
7
43.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
basophil count
5
90.4
educational attainment
8
84.9
osteoprotegerin measurement
1
73.8
brain measurement
0
9.9
66
cortical surface area measurement
0
7
43.2
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
sterile alpha motif domain-containing protein 12
704722
Mouse
MGI:2444518
320679
Dog
sterile alpha motif domain containing 12
VGNC:49882
608931
Horse
sterile alpha motif domain containing 12
VGNC:22673
100057019
Cow
sterile alpha motif domain containing 12
VGNC:34267
783254
Species
Name
OMA
EggNOG
Inparanoid
Macaque
sterile alpha motif domain-containing protein 12
Mouse
Dog
sterile alpha motif domain containing 12
Horse
sterile alpha motif domain containing 12
Cow
sterile alpha motif domain containing 12
Publication Statistics
PubMed Score 21.25
PubMed score by year
PubTator Score 4.75
PubTator score by year
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Related Publications
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PMID
Year
Title