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Tdark
SAMD11
Sterile alpha motif domain-containing protein 11

Protein Summary
Description
May play a role in photoreceptor development.
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.7
gene perturbation
0.58
transcription factor
0.55
virus perturbation
0.55
tissue sample
0.46


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.15   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 19   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.15   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 19   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (35)
SAMD7
Tdark
Novelty:  0.24768324
p_int:  0.999973946
p_ni:  0.000026054
Score:  0.483
Data Source:  BioPlex,STRINGDB
PRR20E
Tdark
p_int:  0.999906204
p_ni:  0.000093232
p_wrong:  5.64e-7
Data Source:  BioPlex
L3MBTL1
Tchem
Family:  TF; Epigenetic
Novelty:  0.02321712
p_int:  0.999793874
p_ni:  0.000206126
Score:  0.181
Data Source:  BioPlex,STRINGDB
SHARPIN
Tbio
Novelty:  0.0197352
p_int:  0.999551449
p_ni:  0.000339642
p_wrong:  0.000108908
Data Source:  BioPlex
HNRNPLL
Tbio
Novelty:  0.0498467
p_int:  0.999355358
p_ni:  0.000642583
p_wrong:  0.000002059
Data Source:  BioPlex
NCAPH2
Tbio
Novelty:  0.12134933
p_int:  0.997252358
p_ni:  0.002320718
p_wrong:  0.000426924
Data Source:  BioPlex
ASB3
Tbio
Novelty:  0.15921018
p_int:  0.973210963
p_ni:  0.02102129
p_wrong:  0.005767746
Score:  0.185
Data Source:  BioPlex,STRINGDB
SIRT6
Tchem
Family:  Epigenetic
Novelty:  0.00155366
p_int:  0.965866181
p_ni:  0.032274342
p_wrong:  0.001859477
Score:  0.154
Data Source:  BioPlex,STRINGDB
OTOP1
Tbio
Novelty:  0.04916753
Score:  0.707
Data Source:  STRINGDB
SEZ6L
Tbio
Novelty:  0.08978367
Score:  0.693
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.3
59.6
apolipoprotein A 1 measurement
2
2
2
52
high density lipoprotein cholesterol measurement
2
2
2
47.4
alkaline phosphatase measurement
1
1
1
46.9
heel bone mineral density
2
1
2
29.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.3
59.6
apolipoprotein A 1 measurement
2
52
high density lipoprotein cholesterol measurement
2
47.4
alkaline phosphatase measurement
1
46.9
heel bone mineral density
2
29.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
sterile alpha motif domain containing 11
VGNC:14083
100608581
Mouse
MGI:2446220
231004
Rat
RGD:1310271
102549710
Dog
sterile alpha motif domain containing 11
VGNC:45849
479576
Horse
sterile alpha motif domain containing 11
VGNC:50759
100061572
Species
Name
OMA
EggNOG
Inparanoid
Chimp
sterile alpha motif domain containing 11
Mouse
Rat
Dog
sterile alpha motif domain containing 11
Horse
sterile alpha motif domain containing 11
Publication Statistics
PubMed Score 4.15
PubMed score by year
PubTator Score 29.29
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title