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Tbio
SALL4
Sal-like protein 4

Protein Summary
Description
Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells. This gene encodes a zinc finger transcription factor thought to play a role in the development of abducens motor neurons. Defects in this gene are a cause of Duane-radial ray syndrome (DRRS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2015]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000217086
  • ENSP00000217086
  • ENSG00000101115
  • ENST00000395997
  • ENSP00000379319

Symbol
  • ZNF797
  • DRRS
  • HSAL4
  • ZNF797
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
biological process
0.76
PubMedID
0.74
biological term
0.72
transcription factor binding site profile
0.69
tissue sample
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 378.71   (req: < 5)
Gene RIFs: 125   (req: <= 3)
Antibodies: 233   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 378.71   (req: >= 5)
Gene RIFs: 125   (req: > 3)
Antibodies: 233   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 12
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0