You are using an outdated browser. Please upgrade your browser to improve your experience.

Tbio
SALL2
Sal-like protein 2

Protein Summary
Description
Probable transcription factor that plays a role in eye development before, during, and after optic fissure closure. This gene encodes a protein containing multiple zinc finger domains. The encoded protein functions in optical fissure closure during development of the eye in the embryo. Mutations in this gene are associated with ocular coloboma. [provided by RefSeq, Jul 2016]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000614342
  • ENSP00000483562
  • ENSG00000165821

Symbol
  • KIAA0360
  • SAL2
  • ZNF795
  • COLB
  • HSAL2
  • Sal-2
  • ZNF795
  • p150(Sal2)
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.88
PubMedID
0.87
tissue sample
0.71
microRNA
0.61
small molecule perturbation
0.6


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 97.51   (req: < 5)
Gene RIFs: 16   (req: <= 3)
Antibodies: 86   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 97.51   (req: >= 5)
Gene RIFs: 16   (req: > 3)
Antibodies: 86   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (60)
VRTN
Tdark
Novelty:  0.07572815
p_int:  0.999976494
p_ni:  0.000023506
Data Source:  BioPlex
HPS1
Tbio
Novelty:  0.44609665
p_int:  0.999957329
p_ni:  0.00004267
p_wrong:  1e-9
Score:  0.204
Data Source:  BioPlex,STRINGDB
RFPL4B
Tdark
Novelty:  2.42779597
p_int:  0.999943063
p_ni:  0.000056932
p_wrong:  5e-9
Data Source:  BioPlex
ASB7
Tbio
Novelty:  0.21883348
p_int:  0.999694795
p_ni:  0.000305205
Data Source:  BioPlex
ATG2B
Tbio
Novelty:  0.04963717
p_int:  0.999615714
p_ni:  0.000384286
Score:  0.377
Data Source:  BioPlex,STRINGDB
CDC16
Tbio
Novelty:  0.00916715
p_int:  0.998774462
p_ni:  0.001225537
p_wrong:  1e-9
Data Source:  BioPlex
ZMYM1
Tdark
Novelty:  0.3860445
p_int:  0.990977553
p_ni:  0.007170237
p_wrong:  0.00185221
Score:  0.295
Data Source:  BioPlex,STRINGDB
PTCD2
Tdark
Novelty:  0.23529342
p_int:  0.990836294
p_ni:  0.009163706
Data Source:  BioPlex
ASB3
Tbio
Novelty:  0.15921018
p_int:  0.961824764
p_ni:  0.038172755
p_wrong:  0.000002481
Data Source:  BioPlex
GFPT2
Tbio
Family:  Enzyme
Novelty:  0.01049877
p_int:  0.951298007
p_ni:  0.048701993
Score:  0.2
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (11)
Find Similar Targets
Items per page:
10
1 – 5 of 5
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Direct Assay (IDA)
NTNU_SB
Inferred from Sequence Alignment (ISA)
NTNU_SB
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations (null)
No disease associations found
GWAS Traits (8)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
1
1
80.1
educational attainment
1
1
1
64.3
body weight
2
2
2
62.5
appendicular lean mass
1
1
1
62.1
diet measurement
1
1
1
61.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body height
1
80.1
educational attainment
1
64.3
body weight
2
62.5
appendicular lean mass
1
62.1
diet measurement
1
61.3
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (3)
1 – 3 of 3
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1354373
50524
Rat
RGD:1309272
305854
Horse
spalt like transcription factor 2
VGNC:22670
100072732
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Horse
spalt like transcription factor 2
Publication Statistics
PubMed Score 97.51
PubMed score by year
PubTator Score 30.06
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title