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Tbio
S100G
Protein S100-G

Protein Summary
Description
This gene encodes calbindin D9K, a vitamin D-dependent calcium-binding protein. This cytosolic protein belongs to a family of calcium-binding proteins that includes calmodulin, parvalbumin, troponin C, and S100 protein. In the intestine, the protein is vitamin D-dependent and its expression correlates with calcium transport activity. The protein may increase Ca2+ absorption by buffering Ca2+ in the cytoplasm and increase ATP-dependent Ca2+ transport in duodenal basolateral membrane vesicles. [provided by RefSeq, Jul 2008]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000380200
  • ENSP00000369547
  • ENSG00000169906

Symbol
  • CABP9K
  • CALB3
  • S100D
  • CABP
  • CABP1
  • CALB3
  • CABP9K
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.85
protein domain
0.85
disease
0.66
chemical
0.57
tissue
0.55


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 337.82   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 64   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 337.82   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 64   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (44)
TRPV6
Tchem
Family:  IC
Novelty:  0.00383629
Score:  0.899
Data Source:  STRINGDB
CALB1
Tbio
Novelty:  0.00037716
Score:  0.764
Data Source:  STRINGDB
TRPV5
Tchem
Family:  IC
Novelty:  0.0055156
Score:  0.758
Data Source:  STRINGDB
ATP2B1
Tbio
Family:  Transporter
Novelty:  0.00706808
Score:  0.724
Data Source:  STRINGDB
VDR
Tclin
Family:  NR
Novelty:  0.00058366
Score:  0.68
Data Source:  STRINGDB
SDF4
Tbio
Novelty:  0.00105893
Score:  0.67
Data Source:  STRINGDB
PVALB
Tbio
Novelty:  0.00024439
Score:  0.616
Data Source:  STRINGDB
PTH
Tbio
Novelty:  0.00003263
Score:  0.593
Data Source:  STRINGDB
CABP2
Tbio
Novelty:  0.08451877
Score:  0.583
Data Source:  STRINGDB
SLC8A1
Tchem
Family:  Transporter
Novelty:  0.0023933
Score:  0.565
Data Source:  STRINGDB
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
S100 calcium binding protein G
VGNC:1196
737870
Macaque
S100 calcium binding protein G
713702
Mouse
MGI:104528
12309
Rat
RGD:2253
24249
Dog
S100 calcium binding protein G
VGNC:49688
607826
Species
Name
OMA
EggNOG
Inparanoid
Chimp
S100 calcium binding protein G
Macaque
S100 calcium binding protein G
Mouse
Rat
Dog
S100 calcium binding protein G
Publication Statistics
PubMed Score 337.82
PubMed score by year
PubTator Score 268.64
PubTator score by year
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Related Publications
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PMID
Year
Title