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Tdark
RWDD4
RWD domain-containing protein 4

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000326397
  • ENSP00000388920
  • ENSG00000182552
  • ENST00000510968
  • ENSP00000426329

Symbol
  • FAM28A
  • RWDD4A
  • FAM28A
  • RWDD4A
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.96
histone modification site profile
0.92
kinase perturbation
0.88
virus perturbation
0.85
disease perturbation
0.83


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.5   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 43   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.5   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 43   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (26)
ZNF330
Tdark
Novelty:  0.32566699
p_int:  1
Score:  0.692
Data Source:  BioPlex,STRINGDB
DRG2
Tbio
Novelty:  0.03293987
Score:  0.874
Data Source:  STRINGDB
DRG1
Tbio
Novelty:  0.32024564
Score:  0.699
Data Source:  STRINGDB
RWDD1
Tbio
Novelty:  0.14946142
Score:  0.682
Data Source:  STRINGDB
EBNA1BP2
Tbio
Novelty:  0.02083466
Score:  0.627
Data Source:  STRINGDB
RWDD2A
Tdark
Novelty:  0.39863218
Score:  0.588
Data Source:  STRINGDB
ZC3H15
Tbio
Novelty:  0.15630592
Score:  0.542
Data Source:  STRINGDB
KRI1
Tbio
Novelty:  0.25087604
Score:  0.539
Data Source:  STRINGDB
ASB15
Tdark
Novelty:  0.11871549
Score:  0.539
Data Source:  STRINGDB
CENPU
Tbio
Novelty:  0.03681625
Score:  0.506
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
1
1
2.2
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
educational attainment
1
2.2
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RWD domain containing 4
VGNC:671
471364
Macaque
RWD domain containing 4
708882
Mouse
MGI:2681000
192174
Rat
RGD:1564132
502084
Dog
RWD domain containing 4
VGNC:45816
403525
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RWD domain containing 4
Macaque
RWD domain containing 4
Mouse
Rat
Dog
RWD domain containing 4
Publication Statistics
PubMed Score 3.50
PubMed score by year
PubTator Score 0.33
PubTator score by year
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Related Publications
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PMID
Year
Title