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Tdark
RWDD2A
RWD domain-containing protein 2A

IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.05   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 62   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 2.05   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 62   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (201)
ATG7
Tchem
Novelty:  0.00120728
p_int:  0.997260945
p_ni:  0.002739055
Score:  0.275
Data Source:  BioPlex,STRINGDB
DDX46
Tbio
Family:  Enzyme
Novelty:  0.02888527
Score:  0.685
Data Source:  STRINGDB
ACIN1
Tbio
Novelty:  0.01675479
Score:  0.679
Data Source:  STRINGDB
RWDD1
Tbio
Novelty:  0.14946142
Score:  0.652
Data Source:  STRINGDB
C6orf163
Tdark
Novelty:  7.76470588
Score:  0.647
Data Source:  STRINGDB
ARGLU1
Tdark
Novelty:  0.28840832
Score:  0.607
Data Source:  STRINGDB
UBE3D
Tbio
Family:  Enzyme
Novelty:  0.44919491
Score:  0.603
Data Source:  STRINGDB
RWDD4
Tdark
Novelty:  0.36794676
Score:  0.588
Data Source:  STRINGDB
UBE2D1
Tbio
Novelty:  0.00865867
Score:  0.585
Data Source:  STRINGDB
UBE2V2
Tbio
Novelty:  0.01112479
Score:  0.576
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (0)
No GO Terms found
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1
0
1.1
31.4
platelet-derived growth factor BB measurement
1
1
1
2.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
0
1.1
31.4
platelet-derived growth factor BB measurement
1
2.9
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
RWD domain containing 2A
694598
Mouse
MGI:1916769
69519
Rat
RGD:1306231
363110
Dog
RWD domain containing 2A
VGNC:45814
481901
Horse
RWD domain containing 2A
VGNC:22635
100065414
Species
Name
OMA
EggNOG
Inparanoid
Macaque
RWD domain containing 2A
Mouse
Rat
Dog
RWD domain containing 2A
Horse
RWD domain containing 2A
Publication Statistics
PubMed Score 2.05
PubMed score by year
PubTator Score 0.33
PubTator score by year
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Related Publications
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PMID
Year
Title