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Tbio
RWDD1
RWD domain-containing protein 1

Protein Summary
Description
Protects DRG2 from proteolytic degradation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000466444
  • ENSP00000420357
  • ENSG00000111832
  • ENST00000487832
  • ENSP00000428778

Symbol
  • DFRP2
  • CGI-24
  • PTD013
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.88
transcription factor binding site profile
0.83
virus perturbation
0.83
histone modification site profile
0.7
disease perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.91   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 114   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 5.91   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 114   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (40)
DRG2
Tbio
Novelty:  0.03293987
p_int:  1
Score:  0.992
Data Source:  BioPlex,STRINGDB
DRG1
Tbio
Novelty:  0.32024564
Score:  0.928
Data Source:  STRINGDB
ZC3H15
Tbio
Novelty:  0.15630592
Score:  0.899
Data Source:  STRINGDB
GCN1
Tbio
Novelty:  0.02721216
Score:  0.85
Data Source:  STRINGDB
PFDN5
Tbio
Novelty:  0.07673574
Score:  0.693
Data Source:  STRINGDB
CLVS2
Tbio
Novelty:  0.95264322
Score:  0.688
Data Source:  STRINGDB
RWDD4
Tdark
Novelty:  0.36794676
Score:  0.682
Data Source:  STRINGDB
HSPBP1
Tbio
Novelty:  0.01176285
Score:  0.676
Data Source:  STRINGDB
UBL7
Tbio
Novelty:  0.20935024
Score:  0.669
Data Source:  STRINGDB
EBNA1BP2
Tbio
Novelty:  0.02083466
Score:  0.666
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
Find Similar Targets
Items per page:
10
1 – 2 of 2
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Inferred from Electronic Annotation (IEA)
Ensembl
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RWD domain containing 1
VGNC:3692
462961
Macaque
RWD domain containing 1
715760
Mouse
MGI:1913771
66521
Rat
RGD:631337
259218
Dog
RWD domain containing 1
VGNC:45813
609552
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RWD domain containing 1
Macaque
RWD domain containing 1
Mouse
Rat
Dog
RWD domain containing 1
Publication Statistics
PubMed Score 5.91
PubMed score by year
PubTator Score 0.20
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title