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Tbio
RUSC2
Iporin

Protein Summary
Description
This gene encodes a RUN and SH3 domain containing protein that interacts with Rab1b and Rab1-binding protein GM130. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000361226
  • ENSP00000355177
  • ENSG00000198853
  • ENST00000455600
  • ENSP00000393922

Symbol
  • KIAA0375
  • MRT61
  • Iporin
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.87
transcription factor
0.87
transcription factor binding site profile
0.87
small molecule perturbation
0.71
transcription factor perturbation
0.68


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.71   (req: < 5)
Gene RIFs: 5   (req: <= 3)
Antibodies: 117   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.71   (req: >= 5)
Gene RIFs: 5   (req: > 3)
Antibodies: 117   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0