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Tbio
RTP1
Receptor-transporting protein 1

Protein Summary
Description
Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000312295
  • ENSP00000311712
  • ENSG00000175077

Symbol
  • Z3CXXC1
  • Z3CXXC1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell line
0.71
microRNA
0.46
tissue sample
0.44
protein domain
0.41
transcription factor
0.4


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.91   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 87   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 40.91   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 87   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (403)
B4GALT6
Tbio
Family:  Enzyme
Novelty:  0.08523889
p_int:  0.963270334
p_ni:  0.013361654
p_wrong:  0.023368012
Data Source:  BioPlex
OR10J5
Tdark
Family:  oGPCR
Novelty:  0.42152783
Score:  0.948
Data Source:  STRINGDB
OR51E2
Tchem
Family:  oGPCR
Novelty:  0.02435259
Score:  0.948
Data Source:  STRINGDB
GNAL
Tbio
Novelty:  0.01757098
Score:  0.945
Data Source:  STRINGDB
OR6B3
Tdark
Family:  oGPCR
Novelty:  8.94430883
Score:  0.941
Data Source:  STRINGDB
OR51E1
Tbio
Family:  oGPCR
Novelty:  0.05230721
Score:  0.936
Data Source:  STRINGDB
OR6P1
Tdark
Family:  oGPCR
Novelty:  11.7597471
Score:  0.935
Data Source:  STRINGDB
OR6B2
Tdark
Family:  oGPCR
Novelty:  0.30964171
Score:  0.935
Data Source:  STRINGDB
OR2L13
Tdark
Family:  oGPCR
Novelty:  0.3071575
Score:  0.934
Data Source:  STRINGDB
OR52I1
Tdark
Family:  oGPCR
Novelty:  0.89795918
Score:  0.932
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (5)
G alpha (s) signalling events (R-HSA-418555)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
G alpha (s) signalling events
Reactome
GPCR downstream signalling
Reactome
Olfactory Signaling Pathway
Reactome
Signal Transduction
Reactome
Signaling by GPCR
Name
Explore in Pharos
Explore in Source
G alpha (s) signalling events
GPCR downstream signalling
Olfactory Signaling Pathway
Signal Transduction
Signaling by GPCR
Viral Interactions (0)
No viral interactions found
Disease Associations ()
No disease associations found
GWAS Traits (1)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
central corneal thickness
1
1
0
1.6
8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
central corneal thickness
0
1.6
8
IDG Resources
No IDG generated resources found
Orthologs (9)
1 – 5 of 9
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
receptor transporter protein 1
VGNC:10338
739400
Macaque
receptor transporter protein 1
708309
Mouse
MGI:2685450
239766
Rat
RGD:1560980
288006
Dog
receptor transporter protein 1
VGNC:45798
488120
Species
Name
OMA
EggNOG
Inparanoid
Chimp
receptor transporter protein 1
Macaque
receptor transporter protein 1
Mouse
Rat
Dog
receptor transporter protein 1
Publication Statistics
PubMed Score 40.91
PubMed score by year
PubTator Score 8.37
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title