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Tbio
RRP7A
Ribosomal RNA-processing protein 7 homolog A

Protein Summary
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.86
kinase perturbation
0.81
tissue
0.63
cellular component
0.59
tissue sample
0.53


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.9   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 120   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.9   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 120   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (268)
WDR46
Tbio
Novelty:  0.19307408
p_int:  0.999981134
p_ni:  0.000018866
Score:  0.998
Data Source:  BioPlex,STRINGDB
NOL6
Tbio
Novelty:  0.10002413
p_int:  0.999865422
p_ni:  0.000134507
p_wrong:  7.1e-8
Score:  0.999
Data Source:  BioPlex,Reactome,STRINGDB
NAP1L5
Tbio
Novelty:  0.10378595
p_int:  0.998975244
p_ni:  0.001024756
Score:  0.527
Data Source:  BioPlex,STRINGDB
DGKZ
Tchem
Family:  Enzyme
Novelty:  0.01312044
p_int:  0.998396853
p_ni:  0.001603147
Data Source:  BioPlex
MECP2
Tchem
Family:  TF
Novelty:  0.00051767
p_int:  0.997888745
p_ni:  0.002111255
Data Source:  BioPlex
ATP4A
Tclin
Family:  Transporter
Novelty:  0.00008783
p_int:  0.997348101
p_ni:  0.00263676
p_wrong:  0.000015139
Score:  0.185
Data Source:  BioPlex,STRINGDB
ZBTB48
Tbio
Family:  TF
Novelty:  0.07020518
p_int:  0.995565528
p_ni:  0.004434472
Data Source:  BioPlex
LRRC46
Tdark
Novelty:  1.159245
p_int:  0.993893299
p_ni:  0.006106652
p_wrong:  5e-8
Score:  0.199
Data Source:  BioPlex,STRINGDB
CRMP1
Tbio
Family:  Enzyme
Novelty:  0.01998451
p_int:  0.992442304
p_ni:  0.007557696
Score:  0.305
Data Source:  BioPlex,STRINGDB
CAMK2A
Tchem
Family:  Kinase
Novelty:  0.00534906
p_int:  0.991875344
p_ni:  0.008123846
p_wrong:  8.1e-7
Score:  0.175
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (6)
Major pathway of rRNA processing in the nucleolus and cytosol (R-HSA-6791226)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 5
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Major pathway of rRNA processing in the nucleolus and cytosol
Reactome
Metabolism of RNA
Reactome
rRNA modification in the nucleus and cytosol
Reactome
rRNA processing
Reactome
rRNA processing in the nucleus and cytosol
Name
Explore in Pharos
Explore in Source
Major pathway of rRNA processing in the nucleolus and cytosol
Metabolism of RNA
rRNA modification in the nucleus and cytosol
rRNA processing
rRNA processing in the nucleus and cytosol
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
influenza A (H1N1)
1
1
0
23.6
62.6
self reported educational attainment
1
1
1
46.5
metabolite measurement
1
1
1
24.5
1
1
0
1
15.8
1
1
0
1
15.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
influenza A (H1N1)
0
23.6
62.6
self reported educational attainment
1
46.5
metabolite measurement
1
24.5
0
1
15.8
0
1
15.8
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ribosomal RNA-processing protein 7 homolog A
457357
Macaque
ribosomal RNA processing 7 homolog A
710471
Mouse
MGI:1922028
74778
Rat
RGD:1311547
362967
Dog
ribosomal RNA processing 7 homolog A
609569
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ribosomal RNA-processing protein 7 homolog A
Macaque
ribosomal RNA processing 7 homolog A
Mouse
Rat
Dog
ribosomal RNA processing 7 homolog A
Publication Statistics
PubMed Score 7.90
PubMed score by year
PubTator Score 0.39
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title