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Tbio
RRP12
RRP12-like protein

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000315563
  • ENSP00000324315
  • ENSG00000052749
  • ENST00000370992
  • ENSP00000360031
  • ENST00000414986
  • ENSP00000414863
  • ENST00000536831
  • ENSP00000446184

Symbol
  • KIAA0690
  • KIAA0690
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
gene perturbation
0.94
hub protein
0.94
interacting protein
0.87
ligand (protein) perturbation
0.83
small molecule perturbation
0.74


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.53   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 52   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 8.53   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 52   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (320)
BYSL
Tbio
Novelty:  0.01919968
p_int:  0.999795495
p_ni:  0.000204505
Score:  0.984
Data Source:  BioPlex,STRINGDB
PRM2
Tbio
Novelty:  0.0050028
p_int:  0.996957559
p_ni:  0.003042441
Data Source:  BioPlex
RPS16
Tbio
Novelty:  0.00261983
p_int:  0.996684087
p_ni:  0.003315913
Data Source:  BioPlex
RPS13
Tbio
Novelty:  0.0019983
p_int:  0.995514863
p_ni:  0.004485137
Score:  0.193
Data Source:  BioPlex,STRINGDB
TNFRSF1A
Tchem
Novelty:  0.00037847
p_int:  0.99419155
p_ni:  0.00580845
Data Source:  BioPlex
RPS14
Tbio
Novelty:  0.00576737
p_int:  0.99218111
p_ni:  0.00781889
Score:  0.234
Data Source:  BioPlex,STRINGDB
RRP8
Tbio
Family:  Enzyme
Novelty:  0.04922797
p_int:  0.990969745
p_ni:  0.009030254
p_wrong:  1e-9
Score:  0.809
Data Source:  BioPlex,STRINGDB
PBXIP1
Tbio
Novelty:  0.15404864
p_int:  0.973621753
p_ni:  0.026378247
Data Source:  BioPlex
GPATCH4
Tdark
Novelty:  1.13040547
p_int:  0.965308988
p_ni:  0.034691012
Score:  0.307
Data Source:  BioPlex,STRINGDB
PRR11
Tbio
Novelty:  0.05077483
p_int:  0.958367292
p_ni:  0.041632708
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (4)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (21)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
3
4
4
97.8
neutrophil count
4
4
5
97.8
myeloid white cell count
3
3
3
95.8
leukocyte count
2
3
3
95.2
monocyte percentage of leukocytes
2
2
2
90.7
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
monocyte count
4
97.8
neutrophil count
5
97.8
myeloid white cell count
3
95.8
leukocyte count
3
95.2
monocyte percentage of leukocytes
2
90.7
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ribosomal RNA processing 12 homolog
VGNC:5718
450649
Macaque
ribosomal RNA processing 12 homolog
705854
Mouse
MGI:2147437
107094
Rat
RGD:1591867
679127
Dog
ribosomal RNA processing 12 homolog
VGNC:45764
608725
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ribosomal RNA processing 12 homolog
Macaque
ribosomal RNA processing 12 homolog
Mouse
Rat
Dog
ribosomal RNA processing 12 homolog
Publication Statistics
PubMed Score 8.53
PubMed score by year
PubTator Score 4.15
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title