Tbio RPS25 40S ribosomal protein S25

Protein Summary

Description

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S25E family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Uniprot Accession IDs

• P62851
• B2R4M7
• P25111

Gene Name

• RPS25

Ensembl ID

• ENST00000527673
• ENSP00000435096
• ENSG00000118181
• ENST00000628770
• ENSP00000486392
• ENSG00000280831

Symbol

• S25

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
disease perturbation	1
interacting protein	1
kinase perturbation	0.97
virus perturbation	0.97
histone modification site profile	0.82

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.56   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 203   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 46.56   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 203   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0