Tbio RPP40 Ribonuclease P protein subunit p40

Protein Summary

Description

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

Uniprot Accession IDs

• O75818
• Q5VX97
• Q8WVK8
• RNaseP protein p40

Gene Name

• RPP40

Ensembl ID

• ENST00000319533
• ENSP00000317998
• ENSG00000124787
• ENST00000380051
• ENSP00000369391

Symbol

• RNASEP1
• RNASEP1
• bA428J1.3

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
histone modification site profile	0.89
kinase perturbation	0.81
virus perturbation	0.76
tissue sample	0.65
transcription factor binding site profile	0.65

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.65   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 70   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.65   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 70   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0