Tbio RPP30 Ribonuclease P protein subunit p30

Protein Summary

Description

Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.

Uniprot Accession IDs

• P78346
• B2R799
• E9PB02
• RNaseP protein p30

Gene Name

• RPP30

Ensembl ID

• ENST00000371703
• ENSP00000360768
• ENSG00000148688
• ENST00000413330
• ENSP00000389182

Symbol

• RNASEP2
• TSG15

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
interacting protein	0.94
histone modification site profile	0.88
ligand (protein) perturbation	0.83
disease perturbation	0.74
microRNA	0.69

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Nuclease / Endoribonuclease / Ribonuclease P Protein Subunit P30

Protein / Nucleic Acid Binding / Rna Binding Protein / Endoribonuclease / Ribonuclease P Protein Subunit P30

Protein / Hydrolase / Ribonuclease P Protein Subunit P30

DTO Classes

Protein / Enzyme / Nuclease / Endoribonuclease / Ribonuclease P Protein Subunit P30

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 165.08   (req: < 5)

Gene RIFs: 4   (req: <= 3)

Antibodies: 74   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 165.08   (req: >= 5)

Gene RIFs: 4   (req: > 3)

Antibodies: 74   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0