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Tdark
RPL22L1
60S ribosomal protein L22-like 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000295830
  • ENSP00000346080
  • ENSG00000163584
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
small molecule perturbation
0.92
microRNA
0.9
transcription factor perturbation
0.84
transcription factor binding site profile
0.8
histone modification site profile
0.77


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.68   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 41   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.68   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 41   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (365)
VMAC
Tdark
Novelty:  0.83333333
p_int:  0.999707272
p_ni:  0.000292716
p_wrong:  1.2e-8
Score:  0.379
Data Source:  BioPlex,STRINGDB
FAAP100
Tdark
Novelty:  0.1698504
p_int:  0.99894341
p_ni:  0.00105659
Score:  0.201
Data Source:  BioPlex,STRINGDB
CCDC85B
Tdark
Novelty:  0.02034018
p_int:  0.998258311
p_ni:  0.001731472
p_wrong:  0.000010217
Score:  0.222
Data Source:  BioPlex,STRINGDB
L3HYPDH
Tdark
Family:  Enzyme
Novelty:  0.35456591
p_int:  0.977496887
p_ni:  0.022503112
p_wrong:  1e-9
Score:  0.209
Data Source:  BioPlex,STRINGDB
P62861
Tbio
Novelty:  0.01170009
Score:  0.997
Data Source:  STRINGDB
RPS24
Tbio
Novelty:  0.01928704
Score:  0.997
Data Source:  STRINGDB
RPS19
Tbio
Novelty:  0.00380084
Score:  0.997
Data Source:  STRINGDB
RPS13
Tbio
Novelty:  0.0019983
Score:  0.997
Data Source:  STRINGDB
RPL14
Tbio
Novelty:  0.01600377
Score:  0.997
Data Source:  STRINGDB
RPL30
Tbio
Novelty:  0.0134194
Score:  0.997
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (33)
Axon guidance (R-HSA-422475)

Click on a row in the table to change the structure displayed.

Find Similar Targets
Items per page:
1 – 5 of 32
Data Source
Name
Explore in Pharos
Explore in Source
Reactome
Axon guidance
Reactome
Cap-dependent Translation Initiation
Reactome
Developmental Biology
Reactome
Disease
Reactome
Eukaryotic Translation Elongation
Name
Explore in Pharos
Explore in Source
Axon guidance
Cap-dependent Translation Initiation
Developmental Biology
Disease
Eukaryotic Translation Elongation
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glucose measurement
2
4
4
95.4
HbA1c measurement
1
2
2
85.4
serum gamma-glutamyl transferase measurement
1
2
2
60.4
IGF-1 measurement
1
1
1
39.6
body mass index
1
1
1
26.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glucose measurement
4
95.4
HbA1c measurement
2
85.4
serum gamma-glutamyl transferase measurement
2
60.4
IGF-1 measurement
1
39.6
body mass index
1
26.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Mouse
MGI:1915278
68028
Rat
RGD:1309517
361923
Dog
ribosomal protein L22 like 1
VGNC:45716
488163
Horse
ribosomal protein L22 like 1
VGNC:22526
100063992
Cow
ribosomal protein L22 like 1
614872
Species
Name
OMA
EggNOG
Inparanoid
Mouse
Rat
Dog
ribosomal protein L22 like 1
Horse
ribosomal protein L22 like 1
Cow
ribosomal protein L22 like 1
Publication Statistics
PubMed Score 6.68
PubMed score by year
PubTator Score 0.62
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title