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Tbio
RPF2
Ribosome production factor 2 homolog

Protein Summary
Description
Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000441448
  • ENSP00000402338
  • ENSG00000197498

Symbol
  • BXDC1
  • BXDC1
  • bA397G5.4
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.91
kinase perturbation
0.88
hub protein
0.85
interacting protein
0.82
transcription factor binding site profile
0.69


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.49   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 155   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 25.49   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 155   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 8
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (362)
CNBP
Tbio
Novelty:  0.00404247
p_int:  0.990495563
p_ni:  0.009504437
Score:  0.363
Data Source:  BioPlex,STRINGDB
ZNF2
Tbio
Family:  TF
Novelty:  0.01062543
p_int:  0.983312789
p_ni:  0.016687211
Data Source:  BioPlex
RRS1
Tbio
Novelty:  0.01643671
p_int:  0.981206044
p_ni:  0.018793956
Score:  0.999
Data Source:  BioPlex,STRINGDB
RBM4
Tbio
Novelty:  0.02034191
p_int:  0.980545034
p_ni:  0.019454966
Score:  0.166
Data Source:  BioPlex,STRINGDB
NOP53
Tbio
Novelty:  0.00353077
p_int:  0.976233716
p_ni:  0.023766284
Score:  0.985
Data Source:  BioPlex,STRINGDB
GPATCH4
Tdark
Novelty:  1.13040547
p_int:  0.972786931
p_ni:  0.027213068
Score:  0.759
Data Source:  BioPlex,STRINGDB
RBM34
Tdark
Novelty:  0.58131282
p_int:  0.960129574
p_ni:  0.039870426
Score:  0.981
Data Source:  BioPlex,STRINGDB
RRP8
Tbio
Family:  Enzyme
Novelty:  0.04922797
p_int:  0.959561528
p_ni:  0.040438472
Score:  0.932
Data Source:  BioPlex,STRINGDB
RPL37A
Tbio
Novelty:  0.03475061
p_int:  0.948296459
p_ni:  0.051703541
Score:  0.701
Data Source:  BioPlex,STRINGDB
KNOP1
Tdark
Novelty:  0.5609503
p_int:  0.947382172
p_ni:  0.052617828
Score:  0.303
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (10)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
UniProtKB
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (2)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
2
1
2
59.8
amino acid measurement
1
1
1
42.3
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
blood metabolite measurement
2
59.8
amino acid measurement
1
42.3
IDG Resources
No IDG generated resources found
Orthologs (15)
1 – 5 of 15
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ribosome production factor 2 homolog
VGNC:11215
462940
Macaque
ribosome production factor 2 homolog
696378
Mouse
MGI:1914489
67239
Rat
RGD:1306906
294436
Dog
ribosome production factor 2 homolog
VGNC:45710
475029
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ribosome production factor 2 homolog
Macaque
ribosome production factor 2 homolog
Mouse
Rat
Dog
ribosome production factor 2 homolog
Publication Statistics
PubMed Score 25.49
PubMed score by year
PubTator Score 3.78
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title