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Tdark
RNF175
RING finger protein 175

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000347063
  • ENSP00000340979
  • ENSG00000145428
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
cell type or tissue
0.68
cellular component
0.53
molecular function
0.49
phenotype
0.46
tissue sample
0.45


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.64   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 81   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.64   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 81   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (21)
RNF186
Tbio
Novelty:  0.15621021
Score:  0.778
Data Source:  STRINGDB
RNF150
Tdark
Novelty:  0.49393737
Score:  0.747
Data Source:  STRINGDB
RNF185
Tbio
Family:  Enzyme
Novelty:  0.23911257
Score:  0.736
Data Source:  STRINGDB
RNF182
Tdark
Family:  Enzyme
Novelty:  0.44540458
Score:  0.706
Data Source:  STRINGDB
ZNRF4
Tbio
Novelty:  0.16505328
Score:  0.675
Data Source:  STRINGDB
RNF183
Tbio
Novelty:  0.34873861
Score:  0.671
Data Source:  STRINGDB
TMEM131L
Tbio
Novelty:  0.60395527
Score:  0.562
Data Source:  STRINGDB
ZBED5
Tdark
Novelty:  0.47929262
Score:  0.528
Data Source:  STRINGDB
MARCH6
Tbio
Family:  Enzyme
Novelty:  0.01818691
Score:  0.513
Data Source:  STRINGDB
RNFT1
Tdark
Novelty:  1.15288082
Score:  0.493
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
1
1
1
77.3
mean corpuscular volume
1
1
1
61.4
reticulocyte measurement
1
1
1
53.7
reticulocyte count
1
1
1
50.6
platelet crit
1
1
1
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean reticulocyte volume
1
77.3
mean corpuscular volume
1
61.4
reticulocyte measurement
1
53.7
reticulocyte count
1
50.6
platelet crit
1
49.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (6)
1 – 5 of 6
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ring finger protein 175
VGNC:672
461555
Macaque
ring finger protein 175
697243
Cow
ring finger protein 175
VGNC:34037
618126
Zebrafish
ZDB-GENE-040426-1104
393278
C. elegans
182681
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ring finger protein 175
Macaque
ring finger protein 175
Cow
ring finger protein 175
Zebrafish
C. elegans
Publication Statistics
PubMed Score 0.64
PubMed score by year
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Related Publications
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0 of 0
PMID
Year
Title