You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
RNF151
RING finger protein 151

Protein Summary
Description
May be involved in acrosome formation of spermatids.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000569714
  • ENSP00000456566
  • ENSG00000179580
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
gene perturbation
0.76
cell type or tissue
0.65
cell line
0.59
PubMedID
0.58


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.79   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 26   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.79   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 26   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (77)
HIST1H1A
Tbio
Novelty:  0.00123818
p_int:  0.999999457
p_ni:  5.43e-7
Data Source:  BioPlex
TNRC18
Tdark
Novelty:  0.32654022
p_int:  0.999869507
p_ni:  0.000130445
p_wrong:  4.8e-8
Data Source:  BioPlex
PNN
Tbio
Novelty:  0.01395394
p_int:  0.999270765
p_ni:  0.000729235
Data Source:  BioPlex
RNPS1
Tbio
Novelty:  0.03203224
p_int:  0.998543922
p_ni:  0.001456078
Score:  0.156
Data Source:  BioPlex,STRINGDB
ZNF16
Tbio
Family:  TF
Novelty:  0.18433365
p_int:  0.997666862
p_ni:  0.002236282
p_wrong:  0.000096856
Data Source:  BioPlex
AFF4
Tbio
Family:  TF
Novelty:  0.02113896
p_int:  0.995869207
p_ni:  0.004130663
p_wrong:  1.3e-7
Data Source:  BioPlex
MORF4L1
Tbio
Family:  Epigenetic
Novelty:  0.01696001
p_int:  0.994498723
p_ni:  0.005501277
Data Source:  BioPlex
MLLT3
Tchem
Novelty:  0.00361056
p_int:  0.994473848
p_ni:  0.00548597
p_wrong:  0.000040183
Data Source:  BioPlex
CLK3
Tchem
Family:  Kinase
Novelty:  0.03466191
p_int:  0.993289602
p_ni:  0.00670946
p_wrong:  9.38e-7
Data Source:  BioPlex
UBTF
Tbio
Family:  TF
Novelty:  0.00421069
p_int:  0.988442368
p_ni:  0.011557627
p_wrong:  5e-9
Data Source:  BioPlex
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations ()
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
1
3
3
92
glomerular filtration rate
2
2
2
78.7
2
3
0
1.1
77.8
hemoglobin measurement
2
1
2
75.6
red blood cell density measurement
1
1
1
71.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
IGF-1 measurement
3
92
glomerular filtration rate
2
78.7
0
1.1
77.8
hemoglobin measurement
2
75.6
red blood cell density measurement
1
71.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
ring finger protein 151
693744
Mouse
MGI:1914754
67504
Rat
RGD:1309302
302977
Dog
ring finger protein 151
VGNC:45640
611018
Horse
ring finger protein 151
VGNC:22446
100068047
Species
Name
OMA
EggNOG
Inparanoid
Macaque
ring finger protein 151
Mouse
Rat
Dog
ring finger protein 151
Horse
ring finger protein 151
Publication Statistics
PubMed Score 0.79
PubMed score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title