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Tdark
RNF150
RING finger protein 150

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000306799
  • ENSP00000304321
  • ENSG00000170153
  • ENST00000420921
  • ENSP00000394581
  • ENST00000507500
  • ENSP00000425568
  • ENST00000515673
  • ENSP00000425840

Symbol
  • KIAA1214
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
trait
0.86
transcription factor binding site profile
0.64
virus perturbation
0.64
disease
0.59
tissue sample
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.82   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 142   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.82   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 142   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (56)
CNN1
Tbio
Novelty:  0.00813104
p_int:  0.828216661
p_ni:  0.171783339
Score:  0.692
Data Source:  BioPlex,STRINGDB
TMEM131L
Tbio
Novelty:  0.60395527
Score:  0.813
Data Source:  STRINGDB
TIGD4
Tdark
Novelty:  1.81608844
Score:  0.798
Data Source:  STRINGDB
OCIAD2
Tbio
Novelty:  0.19380887
Score:  0.75
Data Source:  STRINGDB
RNF175
Tdark
Novelty:  2.00792695
Score:  0.747
Data Source:  STRINGDB
ARFIP1
Tbio
Novelty:  0.20178246
Score:  0.732
Data Source:  STRINGDB
RNF186
Tbio
Novelty:  0.15621021
Score:  0.72
Data Source:  STRINGDB
NDUFC1
Tclin
Family:  Enzyme
Novelty:  0.48303612
Score:  0.714
Data Source:  STRINGDB
SYNPO2
Tbio
Novelty:  0.03313672
Score:  0.711
Data Source:  STRINGDB
GABRB1
Tclin
Family:  IC
Novelty:  0.02895574
Score:  0.698
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
2
2
2
88
platelet count
1
1
1
61
hip circumference
1
2
2
47.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
platelet crit
2
88
platelet count
1
61
hip circumference
2
47.5
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
ring finger protein 150
VGNC:673
461506
Macaque
ring finger protein 150
702799
Mouse
MGI:2443860
330812
Rat
RGD:1304572
364983
Dog
ring finger protein 150
VGNC:45639
607611
Species
Name
OMA
EggNOG
Inparanoid
Chimp
ring finger protein 150
Macaque
ring finger protein 150
Mouse
Rat
Dog
ring finger protein 150
Publication Statistics
PubMed Score 1.82
PubMed score by year
PubTator Score 1.00
PubTator score by year
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Related Publications
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PMID
Year
Title