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Tdark
RNASE10
Inactive ribonuclease-like protein 10

Protein Summary
Description
Secreted proximal epididymal protein required for post-testicular sperm maturation and male fertility. May be involved in sperm adhesion to the egg zona pellucida. Does not have ribonuclease activity (By similarity).
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000328444
  • ENSP00000333358
  • ENSG00000182545
  • ENST00000430083
  • ENSP00000392996

Symbol
  • RAH1
  • RNASE9
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
virus perturbation
0.64
gene perturbation
0.62
phenotype
0.5
cell line
0.49
tissue sample
0.46


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.4   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 25   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 9.4   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 25   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 7
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (12)
TRMT1
Tbio
Family:  Enzyme
Novelty:  0.01795504
p_int:  0.999879023
p_ni:  0.000120956
p_wrong:  2.1e-8
Data Source:  BioPlex
RNASE13
Tbio
Family:  Enzyme
Novelty:  0.05907604
Score:  0.76
Data Source:  STRINGDB
RNASE11
Tdark
Family:  Enzyme
Novelty:  0.32319301
Score:  0.604
Data Source:  STRINGDB
LCN9
Tdark
Novelty:  0.25490072
Score:  0.547
Data Source:  STRINGDB
CST11
Tbio
Novelty:  0.0327324
Score:  0.538
Data Source:  STRINGDB
LCN8
Tbio
Novelty:  0.02098116
Score:  0.485
Data Source:  STRINGDB
BCL2L15
Tbio
Novelty:  0.11260258
Score:  0.474
Data Source:  STRINGDB
TNFAIP6
Tbio
Novelty:  0.0046811
Score:  0.474
Data Source:  STRINGDB
CLGN
Tbio
Novelty:  0.06204915
Score:  0.473
Data Source:  STRINGDB
TPST2
Tbio
Family:  Enzyme
Novelty:  0.02551048
Score:  0.442
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (8)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
InterPro
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mitochondrial DNA measurement
1
1
1
73.6
metabolite measurement
1
1
1
65.6
aspartate aminotransferase measurement
2
1
1
6.8
62.1
1
1
0
1.6
27.3
serum alanine aminotransferase measurement
1
1
0
5.6
21.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mitochondrial DNA measurement
1
73.6
metabolite measurement
1
65.6
aspartate aminotransferase measurement
1
6.8
62.1
0
1.6
27.3
serum alanine aminotransferase measurement
0
5.6
21.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (7)
1 – 5 of 7
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
ribonuclease A family member 10 (inactive)
702870
Mouse
MGI:1922269
75019
Rat
RGD:1310415
305840
Dog
ribonuclease A family member 10 (inactive)
482560
Horse
ribonuclease A family member 10 (inactive)
100033972
Species
Name
OMA
EggNOG
Inparanoid
Macaque
ribonuclease A family member 10 (inactive)
Mouse
Rat
Dog
ribonuclease A family member 10 (inactive)
Horse
ribonuclease A family member 10 (inactive)
Publication Statistics
PubMed Score 9.40
PubMed score by year
PubTator Score 1.33
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title