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Tbio
RMDN2
Regulator of microtubule dynamics protein 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000354545
  • ENSP00000346549
  • ENSG00000115841
  • ENST00000406384
  • ENSP00000386004
  • ENST00000417700
  • ENSP00000392977

Symbol
  • FAM82A
  • FAM82A1
  • RMD2
  • RMD4
  • RMD-2
  • FAM82A
  • BLOCK18
  • FAM82A1
  • PRO34163
  • PYST9371
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.68
trait
0.61
transcription factor
0.59
tissue sample
0.58
phenotype
0.53


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.73   (req: < 5)
Gene RIFs: 4   (req: <= 3)
Antibodies: 162   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.73   (req: >= 5)
Gene RIFs: 4   (req: > 3)
Antibodies: 162   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (21)
VAPB
Tbio
Novelty:  0.00542377
p_int:  0.999999982
p_ni:  1.8e-8
Score:  0.62
Data Source:  BioPlex,STRINGDB
NEUROG3
Tbio
Family:  TF
Novelty:  0.00341077
p_int:  0.999990226
p_ni:  0.000009167
p_wrong:  6.08e-7
Score:  0.263
Data Source:  BioPlex,STRINGDB
VAPA
Tbio
Novelty:  0.00169209
p_int:  0.999986239
p_ni:  0.000013761
Score:  0.465
Data Source:  BioPlex,STRINGDB
ARMC6
Tdark
Novelty:  0.58706267
p_int:  0.999234116
p_ni:  0.000566396
p_wrong:  0.000199489
Data Source:  BioPlex
SLC39A8
Tbio
Family:  Transporter
Novelty:  0.00923197
p_int:  0.997929978
p_ni:  0.000077127
p_wrong:  0.001992895
Score:  0.541
Data Source:  BioPlex,STRINGDB
RMDN3
Tbio
Novelty:  0.05108761
p_int:  0.812182677
p_ni:  0.187817323
Score:  0.91
Data Source:  BioPlex,STRINGDB
ZNF454
Tdark
Family:  TF
Novelty:  1.48640477
Score:  0.726
Data Source:  STRINGDB
ZNF572
Tdark
Family:  TF
Novelty:  4.82078777
Score:  0.726
Data Source:  STRINGDB
ZDHHC19
Tdark
Family:  Enzyme
Novelty:  0.35398354
Score:  0.695
Data Source:  STRINGDB
GCHFR
Tbio
Family:  Enzyme
Novelty:  0.04287433
Score:  0.649
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 6 of 6
GO Term
Evidence
Assigned by
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Direct Assay (IDA)
HPA
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (11)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
2
2
1
1.1
74.6
eosinophil count
2
2
2
63
2
1
1
1.1
57.8
keratinocyte carcinoma
1
1
0
1.1
52.7
frontal fibrosing alopecia
1
1
0
1.6
49.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
1
1.1
74.6
eosinophil count
2
63
1
1.1
57.8
keratinocyte carcinoma
0
1.1
52.7
frontal fibrosing alopecia
0
1.6
49.5
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Macaque
regulator of microtubule dynamics 2
710209
Mouse
MGI:2147043
381110
Rat
RGD:1559836
313840
Cow
regulator of microtubule dynamics 2
VGNC:33992
506362
Xenopus
regulator of microtubule dynamics 2
XB-GENE-951448
779922
Species
Name
OMA
EggNOG
Inparanoid
Macaque
regulator of microtubule dynamics 2
Mouse
Rat
Cow
regulator of microtubule dynamics 2
Xenopus
regulator of microtubule dynamics 2
Publication Statistics
PubMed Score 7.73
PubMed score by year
PubTator Score 13.96
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title