You are using an outdated browser. Please upgrade your browser to improve your experience.

Tdark
RMDN1
Regulator of microtubule dynamics protein 1

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000406452
  • ENSP00000385927
  • ENSG00000176623
  • ENST00000430676
  • ENSP00000409661
  • ENST00000519966
  • ENSP00000428661

Symbol
  • FAM82B
  • RMD1
  • RMD-1
  • CGI-90
  • FAM82B
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
transcription factor perturbation
0.88
tissue sample
0.67
cellular component
0.66
transcription factor binding site profile
0.66
cell line
0.56


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.82   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 127   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.82   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 127   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 0
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (22)
CYP2E1
Tchem
Novelty:  0.00030504
p_int:  0.999853696
p_ni:  0.000142991
p_wrong:  0.000003313
Score:  0.685
Data Source:  BioPlex,STRINGDB
CHIT1
Tchem
Family:  Enzyme
Novelty:  0.00113383
p_int:  0.995746321
p_ni:  0.004247665
p_wrong:  0.000006014
Score:  0.54
Data Source:  BioPlex,STRINGDB
PCYT2
Tbio
Family:  Enzyme
Novelty:  0.03267621
Score:  0.614
Data Source:  STRINGDB
ARMC1
Tbio
Novelty:  0.02018109
Score:  0.596
Data Source:  STRINGDB
TIGD5
Tdark
Novelty:  1.93340494
Score:  0.586
Data Source:  STRINGDB
PTPN2
Tchem
Family:  Enzyme
Novelty:  0.00372891
Score:  0.529
Data Source:  STRINGDB
BECN1
Tbio
Novelty:  0.0003792
Score:  0.517
Data Source:  STRINGDB
MRPL55
Tdark
Novelty:  0.55956177
Score:  0.512
Data Source:  STRINGDB
FAM91A1
Tbio
Novelty:  0.76982657
Score:  0.492
Data Source:  STRINGDB
COMMD5
Tbio
Novelty:  0.16163787
Score:  0.492
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (3)
Find Similar Targets
Items per page:
10
1 – 3 of 3
GO Term
Evidence
Assigned by
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Inferred from Electronic Annotation (IEA)
UniProtKB-KW
Inferred from Electronic Annotation (IEA)
UniProtKB-SubCell
Disease Associations (null)
No disease associations found
GWAS Traits (7)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
2
2
52
visceral adipose tissue measurement
1
1
1
49.2
creatinine measurement
1
1
1
36.4
intelligence
1
1
1
35.5
glomerular filtration rate
1
1
1
33.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
body mass index
2
52
visceral adipose tissue measurement
1
49.2
creatinine measurement
1
36.4
intelligence
1
35.5
glomerular filtration rate
1
33.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
regulator of microtubule dynamics 1
VGNC:13311
735846
Macaque
regulator of microtubule dynamics 1
694237
Mouse
MGI:1913552
66302
Rat
RGD:1563085
500419
Dog
regulator of microtubule dynamics 1
VGNC:45605
477931
Species
Name
OMA
EggNOG
Inparanoid
Chimp
regulator of microtubule dynamics 1
Macaque
regulator of microtubule dynamics 1
Mouse
Rat
Dog
regulator of microtubule dynamics 1
Publication Statistics
PubMed Score 0.82
PubMed score by year
PubTator Score 420.73
PubTator score by year
loading...
Related Publications
Items per page:
0 of 0
PMID
Year
Title