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Tdark
RLF
Zinc finger protein Rlf

Protein Summary
Description
May be involved in transcriptional regulation.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000372771
  • ENSP00000361857
  • ENSG00000117000

Symbol
  • ZN-15L
  • ZNF292L
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
disease perturbation
0.68
cell type or tissue
0.67
transcription factor binding site profile
0.67
cell line
0.66
transcription factor
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.1   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.1   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 10
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (24)
TRIM11
Tbio
Family:  Enzyme
Novelty:  0.02243955
p_int:  0.999996721
p_ni:  0.000003279
Score:  0.255
Data Source:  BioPlex,STRINGDB
MYCL
Tbio
Family:  TF
Novelty:  0.0034508
Score:  0.75
Data Source:  STRINGDB
CCNT2
Tbio
Novelty:  0.04593314
Score:  0.711
Data Source:  STRINGDB
TAB2
Tbio
Family:  Enzyme
Novelty:  0.00635786
Score:  0.613
Data Source:  STRINGDB
ANKRD18B
Tdark
Novelty:  0.64962094
Score:  0.553
Data Source:  STRINGDB
ADGRB2
Tbio
Family:  GPCR
Novelty:  0.06085196
Score:  0.545
Data Source:  STRINGDB
RXFP3
Tchem
Family:  GPCR
Novelty:  0.01844783
Score:  0.544
Data Source:  STRINGDB
WIZ
Tbio
Family:  TF
Novelty:  0.04458547
Score:  0.53
Data Source:  STRINGDB
RALA
Tbio
Family:  Enzyme
Novelty:  0.00257914
Score:  0.516
Data Source:  STRINGDB
ZMAT3
Tbio
Novelty:  0.04765896
Score:  0.488
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
1
1
1
39.6
platelet count
1
1
1
33.1
BMI-adjusted waist circumference
1
1
1
0.8
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted hip circumference
1
39.6
platelet count
1
33.1
BMI-adjusted waist circumference
1
0.8
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (13)
1 – 5 of 13
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
rearranged L-myc fusion
469293
Macaque
rearranged L-myc fusion
693503
Mouse
MGI:1924705
109263
Rat
RGD:1305297
313566
Dog
rearranged L-myc fusion
VGNC:45604
475315
Species
Name
OMA
EggNOG
Inparanoid
Chimp
rearranged L-myc fusion
Macaque
rearranged L-myc fusion
Mouse
Rat
Dog
rearranged L-myc fusion
Publication Statistics
PubMed Score 3.10
PubMed score by year
PubTator Score 65.42
PubTator score by year
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Related Publications
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PMID
Year
Title