RIOK1
Serine/threonine-protein kinase RIO1
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Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
kinase perturbation | 0.98 | ||
molecular function | 0.9 | ||
histone modification site profile | 0.87 | ||
small molecule | 0.8 | ||
transcription factor binding site profile | 0.77 | ||
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
- OR - satisfy the following criterion:
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Target has at least one approved drug - AND - satisfies the preceding conditions
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Data Source | Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|---|
Reactome | Major pathway of rRNA processing in the nucleolus and cytosol | ||||
Reactome | Metabolism of RNA | ||||
Reactome | rRNA processing | ||||
Reactome | rRNA processing in the nucleus and cytosol | ||||
Name | Explore in Pharos | Explore in Source | ||
---|---|---|---|---|
Major pathway of rRNA processing in the nucleolus and cytosol | ||||
Metabolism of RNA | ||||
rRNA processing | ||||
rRNA processing in the nucleus and cytosol | ||||
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
Inferred from Electronic Annotation (IEA) | UniProtKB-KW | |||
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
age at onset | 1 | 1 | 0 | 6 | 35 | ||||
Myopia | 1 | 1 | 0 | 6 | 35 | ||||
refractive error measurement | 1 | 1 | 0 | 6 | 35 | ||||
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
age at onset | 0 | 6 | 35 | ||||
Myopia | 0 | 6 | 35 | ||||
refractive error measurement | 0 | 6 | 35 | ||||
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | RIO kinase 1 | VGNC:11207 | 471847 | |||||
Macaque | RIO kinase 1 | 694461 | ||||||
Mouse | MGI:1918590 | 71340 | ||||||
Rat | RGD:1306086 | 291061 | ||||||
Dog | RIO kinase 1 | 478713 | ||||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | RIO kinase 1 | |||||
Macaque | RIO kinase 1 | |||||
Mouse | ||||||
Rat | ||||||
Dog | RIO kinase 1 | |||||
PMID | Year | Title |
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