Tdark RIMBP2 RIMS-binding protein 2

Protein Summary

Description

Plays a role in the synaptic transmission as bifunctional linker that interacts simultaneously with RIMS1, RIMS2, CACNA1D and CACNA1B.

Uniprot Accession IDs

• O15034
• Q96ID2
• RIM-BP2

Gene Name

• RIMBP2

Ensembl ID

• ENST00000261655
• ENSP00000261655
• ENSG00000060709

Symbol

• KIAA0318
• RBP2
• RBP2
• RIM-BP2
• PPP1R133

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
microRNA	0.84
gene perturbation	0.62
protein domain	0.58
tissue	0.56
cell line	0.54

Protein Classes

No PANTHER Classes or DTO Classes found

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.42   (req: < 5)

Gene RIFs: 2   (req: <= 3)

Antibodies: 40   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 13.42   (req: >= 5)

Gene RIFs: 2   (req: > 3)

Antibodies: 40   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0