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Tdark
RGPD8
RANBP2-like and GRIP domain-containing protein 8

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000302558
  • ENSP00000306637
  • ENSG00000169629

Symbol
  • RANBP2ALPHA
  • RANBP2L1
  • RANBP2L3
  • RGP8
  • RANBP2L1
  • RanBP2alpha
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.92
cell type or tissue
0.72
tissue sample
0.59
microRNA
0.53
protein complex
0.52


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.69   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 5   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.69   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 5   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 3
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (75)
RAN
Tchem
Family:  Enzyme
Novelty:  0.00160888
p_int:  0.999999952
p_ni:  4.8e-8
Score:  0.927
Data Source:  BioPlex,STRINGDB
NUP62
Tbio
Novelty:  0.01432724
p_int:  0.999999839
p_ni:  1.61e-7
Score:  0.484
Data Source:  BioPlex,STRINGDB
NEMP1
Tdark
Novelty:  0.37603456
p_int:  0.999999704
p_ni:  2.96e-7
Score:  0.33
Data Source:  BioPlex,STRINGDB
ESRP1
Tbio
Novelty:  0.02035464
p_int:  0.99999969
p_ni:  3.1e-7
Score:  0.183
Data Source:  BioPlex,STRINGDB
FGFR1OP2
Tbio
Novelty:  0.1082136
p_int:  0.999999379
p_ni:  6.21e-7
Data Source:  BioPlex
RCC1
Tbio
Novelty:  0.00260884
p_int:  0.999999226
p_ni:  7.73e-7
p_wrong:  1e-9
Score:  0.586
Data Source:  BioPlex,STRINGDB
TRAF3IP3
Tbio
Novelty:  0.12180834
p_int:  0.999994765
p_ni:  0.000005235
Data Source:  BioPlex
PSMC5
Tbio
Family:  Enzyme
Novelty:  0.01634039
p_int:  0.999994547
p_ni:  0.000005453
Data Source:  BioPlex
FAM136A
Tdark
Novelty:  0.4050275
p_int:  0.999974792
p_ni:  0.000025208
Data Source:  BioPlex
AKIRIN2
Tbio
Novelty:  0.04603317
p_int:  0.999953293
p_ni:  0.000046707
Score:  0.254
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (7)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations ()
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking status measurement
2
2
3
81.8
smoking initiation
1
1
1
44.2
smoking behaviour measurement
1
1
1
36.5
sex hormone-binding globulin measurement
1
1
1
35
alcohol consumption measurement
1
1
1
6.1
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
smoking status measurement
3
81.8
smoking initiation
1
44.2
smoking behaviour measurement
1
36.5
sex hormone-binding globulin measurement
1
35
alcohol consumption measurement
1
6.1
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 6.69
PubMed score by year
PubTator Score 1.03
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title