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Tdark
RFPL2
Ret finger protein-like 2

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000248980
  • ENSP00000248980
  • ENSG00000128253
  • ENST00000248983
  • ENSP00000248983
  • ENST00000400237
  • ENSP00000383096
  • ENST00000626996
  • ENSP00000486618

Symbol
  • RNF79
  • RNF79
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein domain
0.97
cellular component
0.64
transcription factor
0.56
microRNA
0.45
cell line
0.37


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.25   (req: < 5)
Gene RIFs: 1   (req: <= 3)
Antibodies: 95   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 0.25   (req: >= 5)
Gene RIFs: 1   (req: > 3)
Antibodies: 95   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (33)
RFPL3
Tbio
Novelty:  0.44520296
p_int:  1
Score:  0.291
Data Source:  BioPlex,STRINGDB
BACH1
Tbio
Family:  TF
Novelty:  0.04011328
p_int:  0.996568844
p_ni:  0.003425106
p_wrong:  0.000006051
Score:  0.209
Data Source:  BioPlex,STRINGDB
MIOS
Tdark
Novelty:  0.04252507
p_int:  0.962420077
p_ni:  0.037543918
p_wrong:  0.000036006
Score:  0.181
Data Source:  BioPlex,STRINGDB
PHLPP1
Tchem
Family:  Enzyme
Novelty:  0.00747239
p_int:  0.911673559
p_ni:  0.076313421
p_wrong:  0.01201302
Score:  0.227
Data Source:  BioPlex,STRINGDB
DMWD
Tbio
Novelty:  0.04096001
p_int:  0.908921635
p_ni:  0.091078365
p_wrong:  1e-9
Score:  0.201
Data Source:  BioPlex,STRINGDB
ZNF507
Tdark
Family:  TF
Novelty:  1.0899905
p_int:  0.908657277
p_ni:  0.091342723
Score:  0.217
Data Source:  BioPlex,STRINGDB
RB1
Tchem
Novelty:  0.00063798
p_int:  0.864705395
p_ni:  0.135294351
p_wrong:  2.54e-7
Score:  0.189
Data Source:  BioPlex,STRINGDB
WDR73
Tbio
Novelty:  0.10253438
p_int:  0.845629481
p_ni:  0.154370049
p_wrong:  4.69e-7
Score:  0.253
Data Source:  BioPlex,STRINGDB
DYRK1A
Tchem
Family:  Kinase
Novelty:  0.00226963
p_int:  0.837597141
p_ni:  0.16240285
p_wrong:  9e-9
Score:  0.172
Data Source:  BioPlex,STRINGDB
AHNAK
Tbio
Novelty:  0.01201996
p_int:  0.767387638
p_ni:  0.232612362
Score:  0.181
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (4)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glucose tolerance test
1
1
1
70
glucose-dependent insulinotropic peptide measurement
1
1
1
70
1
1
0
3.7
33.1
diastolic blood pressure
1
1
1
9.5
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
glucose tolerance test
1
70
glucose-dependent insulinotropic peptide measurement
1
70
0
3.7
33.1
diastolic blood pressure
1
9.5
IDG Resources
No IDG generated resources found
Orthologs
No orthologs found
Publication Statistics
PubMed Score 0.25
PubMed score by year
PubTator Score 0.74
PubTator score by year
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Related Publications
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PMID
Year
Title