Protein Summary
Involved in the regulation of the perinuclear actin network and nuclear shape through interaction with filamins. Plays an essential role in actin cytoskeleton formation in developing cartilaginous cells. This locus represents naturally occurring read-through transcription between the neighboring zinc finger protein 664 (Gene ID: 144348) and refilin A (Gene ID: 144347) genes on chromosome 12. The read-through transcript produces a protein that shares sequence identity with the downstream refilin A gene product. [provided by RefSeq, Dec 2016]
- ENST00000324038
- ENSP00000315626
- ENSG00000178882
- ENST00000338359
- ENSP00000345898
- ENST00000389727
- ENSP00000374377
- ENST00000546355
- ENSP00000444080
- FAM101A
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
biological process | 0 | ||
biological term | 0 | ||
cell line | 0 | ||
cell type or tissue | 0 | ||
cellular component | 0 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 20.88 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 98 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 20.88 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 98 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0