Protein Summary
- ENST00000371935
- ENSP00000361003
- ENSG00000148300
- ENST00000371942
- ENSP00000361010
- ENST00000628678
- ENSP00000487504
- ENSG00000280706
- ENST00000630460
- ENSP00000486065
- PMC2
- XPMC2H
- REX4
- XPMC2
- XPMC2H
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor binding site profile | 0.86 | ||
histone modification site profile | 0.8 | ||
kinase perturbation | 0.76 | ||
cell type or tissue | 0.66 | ||
tissue sample | 0.63 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 35.71 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 116 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 35.71 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 116 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Expression Data (0 Tissues)
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)

TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (137)
RBM28
Novelty: 0.13090674
p_int: 0.999432554
p_ni: 0.000567446
Score: 0.786
Data Source: BioPlex,STRINGDB
RRP8
Family: Enzyme
Novelty: 0.04922797
p_int: 0.983185147
p_ni: 0.016814853
Score: 0.813
Data Source: BioPlex,STRINGDB
RPL18
Novelty: 0.01765545
p_int: 0.980883645
p_ni: 0.019116355
Score: 0.24
Data Source: BioPlex,STRINGDB
RPL30
Novelty: 0.0134194
p_int: 0.980151462
p_ni: 0.019848538
Score: 0.269
Data Source: BioPlex,STRINGDB
RBM4
Novelty: 0.02034191
p_int: 0.978994877
p_ni: 0.021005123
Score: 0.159
Data Source: BioPlex,STRINGDB
NPM1
Novelty: 0.0005485
p_int: 0.974412816
p_ni: 0.025587184
Score: 0.306
Data Source: BioPlex,STRINGDB
RPL14
Novelty: 0.01600377
p_int: 0.973857288
p_ni: 0.026142712
Score: 0.265
Data Source: BioPlex,STRINGDB
RBM34
Novelty: 0.58131282
p_int: 0.95998753
p_ni: 0.04001247
Score: 0.717
Data Source: BioPlex,STRINGDB
PPAN
Novelty: 0.01063709
p_int: 0.954629293
p_ni: 0.045370707
Score: 0.724
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (8)
Functions (3)
Components (3)
Processes (2)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from High Throughput Direct Assay (HDA) | UniProtKB | |||
Non-traceable Author Statement (NAS) | UniProtKB | |||
Inferred from Electronic Annotation (IEA) | InterPro | |||
Disease Associations (null)
GWAS Traits (28)
Items per page:
1 – 5 of 28
GWAS Trait | EFO ID | ENSG ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|---|
total cholesterol measurement | 1 | 5 | 5 | 96.8 | ||||||
total cholesterol measurement | 1 | 5 | 5 | 96.8 | ||||||
a disintegrin and metalloproteinase with thrombospondin motifs 13 | 1 | 3 | 0 | 7.1 | 96.4 | |||||
a disintegrin and metalloproteinase with thrombospondin motifs 13 | 1 | 3 | 0 | 7.1 | 96.4 | |||||
low density lipoprotein cholesterol measurement | 1 | 4 | 4 | 95.7 | ||||||
Items per page:
1 – 5 of 28
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
total cholesterol measurement | 5 | 96.8 | |||||
total cholesterol measurement | 5 | 96.8 | |||||
a disintegrin and metalloproteinase with thrombospondin motifs 13 | 0 | 7.1 | 96.4 | ||||
a disintegrin and metalloproteinase with thrombospondin motifs 13 | 0 | 7.1 | 96.4 | ||||
low density lipoprotein cholesterol measurement | 4 | 95.7 | |||||
Find similar targets by:
IDG Resources
Orthologs (11)
1 – 5 of 11
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | REX4 homolog, 3'-5' exonuclease | VGNC:53291 | 473152 | |||||
Macaque | REX4 homolog, 3'-5' exonuclease | 713816 | ||||||
Mouse | MGI:2684957 | 227656 | ||||||
Rat | RGD:1306220 | 311826 | ||||||
Dog | REX4 homolog, 3'-5' exonuclease | VGNC:45491 | 491271 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | REX4 homolog, 3'-5' exonuclease | |||||
Macaque | REX4 homolog, 3'-5' exonuclease | |||||
Mouse | ||||||
Rat | ||||||
Dog | REX4 homolog, 3'-5' exonuclease | |||||
Publication Statistics
PubMed Score 35.71
PubMed score by year
PubTator Score 3.24
PubTator score by year
Related Publications
Text Mined References (17)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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