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Tdark
REXO1
RNA exonuclease 1 homolog

Protein Summary
Description
Seems to have no detectable effect on transcription elongation in vitro.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000170168
  • ENSP00000170168
  • ENSG00000079313

Symbol
  • ELOABP1
  • KIAA1138
  • TCEB3BP1
  • REX1
  • ELOABP1
  • EloA-BP1
  • TCEB3BP1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
kinase perturbation
0.71
cell line
0.69
tissue sample
0.66
transcription factor binding site profile
0.63
cell type or tissue
0.61


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 173   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 173   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
AP2M1
Tbio
Novelty:  0.00769368
p_int:  0.99999909
p_ni:  2.06e-7
p_wrong:  7.05e-7
Score:  0.191
Data Source:  BioPlex,STRINGDB
REXO2
Tbio
Family:  Enzyme
Novelty:  0.0114609
Score:  0.964
Data Source:  STRINGDB
REXO5
Tdark
Family:  Enzyme
Novelty:  0.8782494
Score:  0.845
Data Source:  STRINGDB
TCEA1
Tbio
Novelty:  0.00547888
Score:  0.828
Data Source:  STRINGDB
ELOA
Tbio
Novelty:  0.04334224
Score:  0.819
Data Source:  STRINGDB
EXOSC10
Tbio
Novelty:  0.00335571
Score:  0.762
Data Source:  STRINGDB
ABHD17A
Tbio
Family:  Enzyme
Novelty:  0.26144756
Score:  0.748
Data Source:  STRINGDB
DUS3L
Tbio
Family:  Enzyme
Novelty:  0.24952542
Score:  0.718
Data Source:  STRINGDB
EXO1
Tbio
Family:  Enzyme
Novelty:  0.00130104
Score:  0.698
Data Source:  STRINGDB
SCAMP4
Tbio
Novelty:  0.20081295
Score:  0.674
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (18)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
1
2
2
86.7
mean reticulocyte volume
1
2
2
86.4
body mass index
4
3
4
83.8
mean corpuscular hemoglobin concentration
1
1
1
76.5
reticulocyte measurement
3
1
3
68.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
mean corpuscular volume
2
86.7
mean reticulocyte volume
2
86.4
body mass index
4
83.8
mean corpuscular hemoglobin concentration
1
76.5
reticulocyte measurement
3
68.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RNA exonuclease 1 homolog
VGNC:12076
455555
Macaque
RNA exonuclease 1 homolog
708931
Mouse
MGI:1914182
66932
Rat
RGD:1309872
314630
Dog
RNA exonuclease 1 homolog
476752
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RNA exonuclease 1 homolog
Macaque
RNA exonuclease 1 homolog
Mouse
Rat
Dog
RNA exonuclease 1 homolog
Publication Statistics
PubMed Score 4.00
PubMed score by year
PubTator Score 67.35
PubTator score by year
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Related Publications
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PMID
Year
Title