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Tbio
REEP2
Receptor expression-enhancing protein 2

Protein Summary
Description
Required for endoplasmic reticulum (ER) network formation, shaping and remodeling. May enhance the cell surface expression of odorant receptors (By similarity). This gene encodes a member of the receptor expression enhancing protein family. Studies of a related gene in mouse suggest that the encoded protein is found in the cell membrane and enhances the function of sweet taste receptors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000254901
  • ENSP00000254901
  • ENSG00000132563
  • ENST00000378339
  • ENSP00000367590

Symbol
  • C5orf19
  • SGC32445
  • SPG72
  • Yip2d
  • C5orf19
  • SGC32445
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.81
cellular component
0.77
gene perturbation
0.63
tissue sample
0.58
phenotype
0.52


Protein Classes
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.23   (req: < 5)
Gene RIFs: 3   (req: <= 3)
Antibodies: 330   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 6.23   (req: >= 5)
Gene RIFs: 3   (req: > 3)
Antibodies: 330   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 6
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0