Protein Summary
May act as a component of a corepressor complex that represses transcription.
- ENST00000367005
- ENSP00000355972
- ENSG00000117625
- ENST00000367006
- ENSP00000355973
- ENST00000419091
- ENSP00000413929
- ENST00000452621
- ENSP00000398558
- KIAA1343
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
transcription factor perturbation | 0.96 | ||
histone modification site profile | 0.91 | ||
ligand (protein) perturbation | 0.83 | ||
transcription factor binding site profile | 0.75 | ||
cell type or tissue | 0.7 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.94 (req: < 5)
Gene RIFs: 2 (req: <= 3)
Antibodies: 93 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 3.94 (req: >= 5)
Gene RIFs: 2 (req: > 3)
Antibodies: 93 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 5
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

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GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (55)
HMG20A
Family: TF
Novelty: 0.11994252
p_int: 0.999991787
p_ni: 0.000008213
Score: 0.86
Data Source: BioPlex,STRINGDB
HMG20B
Family: TF
Novelty: 0.05983143
p_int: 0.99981279
p_ni: 0.00018721
Score: 0.888
Data Source: BioPlex,STRINGDB
HDAC1
Family: Epigenetic
Novelty: 0.00065244
p_int: 0.999341363
p_ni: 0.000658637
Score: 0.663
Data Source: BioPlex,STRINGDB
ZSCAN5A
Family: TF
Novelty: 2.15267128
p_int: 0.997545856
p_ni: 0.002454144
Score: 0.161
Data Source: BioPlex,STRINGDB
SNAI1
Family: TF
Novelty: 0.00040495
p_int: 0.996467714
p_ni: 0.003532286
Score: 0.781
Data Source: BioPlex,STRINGDB
ECE2
Family: Enzyme
Novelty: 0.03234301
p_int: 0.996305947
p_ni: 0.003694053
Score: 0.211
Data Source: BioPlex,STRINGDB
CTBP1
Novelty: 0.00243818
p_int: 0.995518744
p_ni: 0.004481256
Score: 0.272
Data Source: BioPlex,STRINGDB
DCAF12L2
Novelty: 2.92107204
p_int: 0.987174926
p_ni: 0.012825074
Score: 0.208
Data Source: BioPlex,STRINGDB
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (8)
Functions (5)
Components (3)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Inferred from Sequence Alignment (ISA) | NTNU_SB | |||
Disease Associations ()
GWAS Traits (8)
Items per page:
1 – 5 of 8
GWAS Trait | EFO ID | Study Count | SNP Count | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|---|---|
self reported educational attainment | 2 | 2 | 1 | 5.6 | 49.1 | ||||
platelet crit | 1 | 1 | 1 | 35 | |||||
mean reticulocyte volume | 1 | 1 | 1 | 34.9 | |||||
mean corpuscular volume | 1 | 1 | 1 | 29.8 | |||||
household income | 1 | 1 | 1 | 11.3 | |||||
Items per page:
1 – 5 of 8
GWAS Trait | EFO ID | Beta Count | Odds Ratio | Evidence (Mean Rank Score) | Provenance | ||
---|---|---|---|---|---|---|---|
self reported educational attainment | 1 | 5.6 | 49.1 | ||||
platelet crit | 1 | 35 | |||||
mean reticulocyte volume | 1 | 34.9 | |||||
mean corpuscular volume | 1 | 29.8 | |||||
household income | 1 | 11.3 | |||||
Find similar targets by:
IDG Resources
Orthologs (13)
1 – 5 of 13
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Chimp | REST corepressor 3 | VGNC:1487 | 457710 | |||||
Macaque | REST corepressor 3 | 712037 | ||||||
Mouse | MGI:2441920 | 214742 | ||||||
Rat | RGD:1593864 | 684192 | ||||||
Dog | REST corepressor 3 | VGNC:45448 | 480018 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Chimp | REST corepressor 3 | |||||
Macaque | REST corepressor 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | REST corepressor 3 | |||||
Publication Statistics
PubMed Score 3.94
PubMed score by year
PubTator Score 1.38
PubTator score by year
Related Publications
Text Mined References (19)
GeneRif Annotations (2)
Items per page:
0 of 0
PMID | Year | Title |
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