Protein Summary
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
- ENST00000374393
- ENSP00000363514
- ENSG00000117602
- ENST00000374395
- ENSP00000363516
- ENST00000412742
- ENSP00000391912
- ENST00000425530
- ENSP00000409540
- ENST00000436717
- ENSP00000414447
- ENST00000538532
- ENSP00000445401
- ENST00000610732
- ENSP00000479300
- ENST00000616511
- ENSP00000478174
- ENST00000618490
- ENSP00000484519
- ENST00000630217
- ENSP00000486836
- DSCR1L2
- RCN3
- MCIP3
- hRCN3
- DSCR1L2
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
---|---|---|---|
cell type or tissue | 0.86 | ||
transcription factor perturbation | 0.84 | ||
small molecule perturbation | 0.65 | ||
histone modification site profile | 0.64 | ||
disease perturbation | 0.62 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 9.61 (req: < 5)
Gene RIFs: 8 (req: <= 3)
Antibodies: 238 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 9.61 (req: >= 5)
Gene RIFs: 8 (req: > 3)
Antibodies: 238 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 7
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
Related Tools

GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.

GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.

ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
Active Ligands (0)
Protein-Protein Interactions (43)
PPP3R1
Novelty: 0.00263264
p_int: 0.999999874
p_ni: 1.24e-7
p_wrong: 2e-9
Score: 0.922
Data Source: BioPlex,STRINGDB
ARMT1
Family: Enzyme
Novelty: 0.19632869
p_int: 0.999997541
p_ni: 0.000002459
Score: 0.214
Data Source: BioPlex,STRINGDB
PPP3CB
Family: Enzyme
Novelty: 0.02156713
p_int: 0.999887007
p_ni: 0.000112993
Score: 0.922
Data Source: BioPlex,STRINGDB
SMYD3
Family: Epigenetic
Novelty: 0.01040802
p_int: 0.9960711
p_ni: 0.003548159
p_wrong: 0.000380741
Score: 0.207
Data Source: BioPlex,STRINGDB
CDK4
Family: Kinase
Novelty: 0.00036742
p_int: 0.967655763
p_ni: 0.032344237
p_wrong: 1e-9
Score: 0.424
Data Source: BioPlex,STRINGDB
PLS1
Novelty: 0.00538817
p_int: 0.771574602
p_ni: 0.228425385
p_wrong: 1.3e-8
Data Source: BioPlex
Nearest Tclin Targets
Pathways (0)
Viral Interactions (0)
Gene Ontology Terms (8)
Functions (4)
Components (1)
Processes (3)
GO Term | Evidence | Assigned by | ||
---|---|---|---|---|
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Physical Interaction (IPI) | UniProtKB | |||
Inferred from Biological aspect of Ancestor (IBA) | GO_Central | |||
Traceable Author Statement (TAS) | ProtInc | |||
Disease Associations ()
GWAS Traits (0)
Find similar targets by:
IDG Resources
Orthologs (13)
1 – 5 of 13
Species | Name | Source ID | Gene ID | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|---|---|
Macaque | RCAN family member 3 | 719315 | ||||||
Mouse | MGI:1858220 | 53902 | ||||||
Rat | RGD:1311826 | 362627 | ||||||
Dog | RCAN family member 3 | VGNC:45438 | 487369 | |||||
Horse | RCAN family member 3 | VGNC:22264 | 100071487 | |||||
Species | Name | OMA | EggNOG | Inparanoid | ||
---|---|---|---|---|---|---|
Macaque | RCAN family member 3 | |||||
Mouse | ||||||
Rat | ||||||
Dog | RCAN family member 3 | |||||
Horse | RCAN family member 3 | |||||
Publication Statistics
PubMed Score 9.61
PubMed score by year
PubTator Score 9.63
PubTator score by year
Related Publications
Text Mined References (17)
GeneRif Annotations (8)
Items per page:
0 of 0
PMID | Year | Title |
---|