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Tdark
RBMXL1
RNA binding motif protein, X-linked-like-1

Protein Summary
Description
RNA-binding protein which may be involved in pre-mRNA splicing. This gene represents a retrogene of RNA binding motif protein, X-linked (RBMX), which is located on chromosome X. While all introns in the coding sequence have been processed out compared to the RBMX locus, the ORF is intact and there is specific evidence for transcription at this location. The preservation of the ORF by purifying selection in all Old World monkeys carrying it suggests that this locus is likely to be functional, possibly during male meiosis when X chromosomal genes are silenced or during haploid stages of spermatogenesis. This gene shares 5' exon structure with the cysteine conjugate-beta lyase 2 locus on chromosome 1, but the coding sequences are non-overlapping. Alternative splicing results in two transcript variants. [provided by RefSeq, Jun 2009]
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000321792
  • ENSP00000318415
  • ENSG00000213516
  • ENST00000399794
  • ENSP00000446099

Symbol
  • RBM1
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
protein complex
0.99
co-expressed gene
0.76
histone modification site profile
0.73
kinase perturbation
0.71
cell line
0.64


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.25   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 76   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.25   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 76   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 4
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (29)
SNRNP70
Tbio
Novelty:  0.00116631
p_int:  0.999999644
p_ni:  3.56e-7
Data Source:  BioPlex
APOBEC3D
Tbio
Novelty:  0.01102619
p_int:  0.999999222
p_ni:  7.78e-7
Score:  0.363
Data Source:  BioPlex,STRINGDB
ELAVL2
Tbio
Novelty:  0.00370708
p_int:  0.999997497
p_ni:  0.000002503
Score:  0.513
Data Source:  BioPlex,STRINGDB
SFPQ
Tbio
Novelty:  0.01207637
p_int:  0.999987701
p_ni:  0.000012299
Score:  0.549
Data Source:  BioPlex,STRINGDB
FBXW11
Tbio
Novelty:  0.0715377
p_int:  0.999975073
p_ni:  0.000024927
Data Source:  BioPlex
LARP4B
Tbio
Novelty:  0.11363794
p_int:  0.999904431
p_ni:  0.000095569
Data Source:  BioPlex
SYNCRIP
Tbio
Novelty:  0.01479381
p_int:  0.999748675
p_ni:  0.000251325
Score:  0.718
Data Source:  BioPlex,STRINGDB
CLK2
Tchem
Family:  Kinase
Novelty:  0.13068449
p_int:  0.999724547
p_ni:  0.000275452
p_wrong:  1e-9
Score:  0.635
Data Source:  BioPlex,STRINGDB
RBM47
Tbio
Novelty:  0.04787234
p_int:  0.999469831
p_ni:  0.000530169
Data Source:  BioPlex
ILF2
Tbio
Novelty:  0.01598188
p_int:  0.999469395
p_ni:  0.000530605
Score:  0.2
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (6)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from Biological aspect of Ancestor (IBA)
GO_Central
Disease Associations (null)
No disease associations found
GWAS Traits (5)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
1
1
1
49.5
serum gamma-glutamyl transferase measurement
1
1
1
48.5
blood urea nitrogen measurement
1
1
1
21.5
hemoglobin measurement
1
1
1
10.9
lymphocyte count
1
1
1
8.9
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
BMI-adjusted waist circumference
1
49.5
serum gamma-glutamyl transferase measurement
1
48.5
blood urea nitrogen measurement
1
21.5
hemoglobin measurement
1
10.9
lymphocyte count
1
8.9
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (5)
1 – 5 of 5
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Opossum
RNA binding motif protein, X-linked
100379645
Chicken
RNA binding motif protein, X-linked
CGNC:51674
422248
Anole lizard
RNA binding motif protein, X-linked
100556017
Xenopus
RNA binding motif protein, X-linked
XB-GENE-5733378
100135403
Zebrafish
ZDB-GENE-030131-579
321860
Species
Name
OMA
EggNOG
Inparanoid
Opossum
RNA binding motif protein, X-linked
Chicken
RNA binding motif protein, X-linked
Anole lizard
RNA binding motif protein, X-linked
Xenopus
RNA binding motif protein, X-linked
Zebrafish
Publication Statistics
PubMed Score 1.25
PubMed score by year
PubTator Score 10.74
PubTator score by year
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Related Publications
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0 of 0
PMID
Year
Title