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Tdark
RBM42
RNA-binding protein 42

Protein Summary
Description
Binds (via the RRM domain) to the 3'-untranslated region (UTR) of CDKN1A mRNA.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000262633
  • ENSP00000262633
  • ENSG00000126254
  • ENST00000588161
  • ENSP00000466044
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.89
interacting protein
0.89
disease perturbation
0.79
gene perturbation
0.71
tissue sample
0.65


Protein Classes
No PANTHER Classes or DTO Classes found
IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.06   (req: < 5)
Gene RIFs: 2   (req: <= 3)
Antibodies: 131   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 3.06   (req: >= 5)
Gene RIFs: 2   (req: > 3)
Antibodies: 131   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 2
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Expression Data (0 Tissues)
No expression data found
Related Tools
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (95)
CAMK2G
Tchem
Family:  Kinase
Novelty:  0.04642387
p_int:  0.999965389
p_ni:  0.000034611
Score:  0.313
Data Source:  BioPlex,STRINGDB
CAMK2B
Tchem
Family:  Kinase
Novelty:  0.00793595
p_int:  0.999962216
p_ni:  0.000037784
Data Source:  BioPlex
CAMK2D
Tchem
Family:  Kinase
Novelty:  0.02326864
p_int:  0.999899659
p_ni:  0.000100341
Data Source:  BioPlex
SNRNP27
Tbio
Novelty:  0.0175187
p_int:  0.999879163
p_ni:  0.000120835
p_wrong:  2e-9
Score:  0.159
Data Source:  BioPlex,STRINGDB
RBM45
Tbio
Novelty:  0.06739873
p_int:  0.999800312
p_ni:  0.000199679
p_wrong:  9e-9
Data Source:  BioPlex
RAB11B
Tbio
Family:  Enzyme
Novelty:  0.00557558
p_int:  0.999174617
p_ni:  0.000825383
Data Source:  BioPlex
NGRN
Tbio
Novelty:  0.11162143
p_int:  0.997200545
p_ni:  0.002799455
Data Source:  BioPlex
PTCD1
Tdark
Novelty:  0.17182155
p_int:  0.993811041
p_ni:  0.006188959
Score:  0.183
Data Source:  BioPlex,STRINGDB
TRUB2
Tdark
Family:  Enzyme
Novelty:  0.4130414
p_int:  0.993716799
p_ni:  0.006283201
Data Source:  BioPlex
QKI
Tbio
Novelty:  0.00966983
p_int:  0.988994092
p_ni:  0.011005906
p_wrong:  2e-9
Score:  0.387
Data Source:  BioPlex,STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (5)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations ()
No disease associations found
GWAS Traits (6)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum albumin measurement
1
1
1
69.8
serum alanine aminotransferase measurement
2
1
1
6.9
66.8
calcium measurement
1
1
1
64.9
platelet count
2
2
2
55.8
eosinophil percentage of leukocytes
1
1
1
37.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
serum albumin measurement
1
69.8
serum alanine aminotransferase measurement
1
6.9
66.8
calcium measurement
1
64.9
platelet count
2
55.8
eosinophil percentage of leukocytes
1
37.6
Find similar targets by:
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RNA binding motif protein 42
VGNC:2271
468839
Macaque
RNA binding motif protein 42
709852
Mouse
MGI:1915285
68035
Rat
RGD:1306184
361545
Horse
RNA binding motif protein 42
VGNC:22245
100051102
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RNA binding motif protein 42
Macaque
RNA binding motif protein 42
Mouse
Rat
Horse
RNA binding motif protein 42
Publication Statistics
PubMed Score 3.06
PubMed score by year
PubTator Score 1.63
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title