Tbio RBM19 Probable RNA-binding protein 19

Protein Summary

Description

Plays a role in embryo pre-implantation development. This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009]

Uniprot Accession IDs

• Q9Y4C8
• A8K5X9
• Q9BPY6
• Q9UFN5

Gene Name

• RBM19

Ensembl ID

• ENST00000261741
• ENSP00000261741
• ENSG00000122965
• ENST00000392561
• ENSP00000376344
• ENST00000545145
• ENSP00000442053

Symbol

• KIAA0682
• Mrd1

Knowledge Table

Most Knowledge About	Knowledge Value (0 to 1 scale)
virus perturbation	0.94
histone modification site profile	0.88
transcription factor perturbation	0.84
interacting protein	0.81
transcription factor binding site profile	0.78

Protein Classes

PANTHER Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Mrna Processing Factor / Mrna Splicing Factor / Probable Rna-binding Protein 19

DTO Classes

Protein / Nucleic Acid Binding / Rna Binding Protein / Mrna Processing Factor / Mrna Splicing Factor / Probable Rna-binding Protein 19

IDG Development Level Summary

Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.81   (req: < 5)

Gene RIFs: 5   (req: <= 3)

Antibodies: 49   (req: <= 50)

Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 7.81   (req: >= 5)

Gene RIFs: 5   (req: > 3)

Antibodies: 49   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 5

Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0

Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0