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Tdark
RBM12B
RNA-binding protein 12B

Protein Summary
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000399300
  • ENSP00000382239
  • ENSG00000183808

Symbol
  • MGC:33837
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
microRNA
0.84
transcription factor binding site profile
0.74
cellular component
0.64
transcription factor
0.63
cell type or tissue
0.62


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.14   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 36   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 1.14   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 36   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Term: 1
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (4)
Target Illumination GWAS Analytics (TIGA)
Thumbnail image for Target Illumination GWAS Analytics (TIGA)
TIGA scores and ranks GWAS discovered associations according to the quantity and quality of the evidence supporting the association.
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (45)
EIF4B
Tbio
Novelty:  0.00665561
p_int:  1
Data Source:  BioPlex
PDZRN3
Tbio
Family:  Enzyme
Novelty:  0.06663842
p_int:  0.999946044
p_ni:  0.000053954
p_wrong:  2e-9
Data Source:  BioPlex
RNF20
Tbio
Family:  Enzyme
Novelty:  0.01238827
p_int:  0.99969103
p_ni:  0.00030897
Data Source:  BioPlex
AURKB
Tchem
Family:  Kinase
Novelty:  0.00100972
p_int:  0.999684635
p_ni:  0.000002697
p_wrong:  0.000312667
Score:  0.722
Data Source:  BioPlex,STRINGDB
RNF40
Tbio
Family:  Enzyme
Novelty:  0.07038528
p_int:  0.882644327
p_ni:  0.117355669
p_wrong:  3e-9
Data Source:  BioPlex
CPNE1
Tbio
Novelty:  0.04921263
Score:  0.679
Data Source:  STRINGDB
UBE2O
Tbio
Novelty:  0.07084123
Score:  0.663
Data Source:  STRINGDB
CPNE3
Tbio
Novelty:  0.06125038
Score:  0.655
Data Source:  STRINGDB
CHEK2
Tchem
Family:  Kinase
Novelty:  0.00068355
Score:  0.642
Data Source:  STRINGDB
HNRNPH1
Tbio
Novelty:  0.01273351
Score:  0.64
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Viral Interactions (0)
No viral interactions found
Gene Ontology Terms (1)
Find Similar Targets
Items per page:
10
1 – 1 of 1
GO Term
Evidence
Assigned by
Inferred from High Throughput Direct Assay (HDA)
UniProtKB
Disease Associations (null)
No disease associations found
GWAS Traits (3)
GWAS Trait
EFO ID
Study Count
SNP Count
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neuroticism measurement
1
1
1
7.3
wellbeing measurement
3
1
3
6.6
depressive symptom measurement
1
1
1
6.6
GWAS Trait
EFO ID
Beta Count
Odds Ratio
Evidence (Mean Rank Score)
Provenance
neuroticism measurement
1
7.3
wellbeing measurement
3
6.6
depressive symptom measurement
1
6.6
IDG Resources
No IDG generated resources found
Orthologs (11)
1 – 5 of 11
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RNA binding motif protein 12B
VGNC:809
472818
Macaque
RNA binding motif protein 12B
698382
Mouse
MGI:1919647
72397
Mouse
MGI:1924854
77604
Rat
RGD:1307658
313069
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RNA binding motif protein 12B
Macaque
RNA binding motif protein 12B
Mouse
Mouse
Rat
Publication Statistics
PubMed Score 1.14
PubMed score by year
PubTator Score 0.06
PubTator score by year
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Related Publications
Items per page:
0 of 0
PMID
Year
Title