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Tbio
RBM11
Splicing regulator RBM11

Protein Summary
Description
Tissue-specific splicing factor with potential implication in the regulation of alternative splicing during neuron and germ cell differentiation. Antagonizes SRSF1-mediated BCL-X splicing. May affect the choice of alternative 5' splice sites by binding to specific sequences in exons and antagonizing the SR protein SRSF1.
Uniprot Accession IDs
Gene Name
Ensembl ID
  • ENST00000400577
  • ENSP00000383421
  • ENSG00000185272
Illumination Graph
Knowledge Table
Most Knowledge About
Knowledge Value (0 to 1 scale)
histone modification site profile
0.74
gene perturbation
0.71
virus perturbation
0.68
tissue sample
0.65
molecular function
0.56


IDG Development Level Summary
Tdark

These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.62   (req: < 5)
Gene RIFs: 0   (req: <= 3)
Antibodies: 127   (req: <= 50)
Tbio

These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:

Pubmed score: 4.62   (req: >= 5)
Gene RIFs: 0   (req: > 3)
Antibodies: 127   (req: > 50)

- OR - satisfy the following criterion:

Gene Ontology Terms: 9
Tchem

Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions

Active Ligand: 0
Tclin

Target has at least one approved drug - AND - satisfies the preceding conditions

Active Drug: 0
Expression Data (0 Tissues)
No expression data found
Protein Sequence and Structure
Residue Counts
Protein Sequence
ProtVista Viewer
Related Tools (3)
GENEVA
Thumbnail image for GENEVA
GENEVA (GENe Expression Variance Analysis) allows you to identify RNA-sequencing datasets from the Gene Expression Omnibus (GEO) that contain conditions modulating a gene or a gene signature.
GlyGen
Thumbnail image for GlyGen
GlyGen is a data integration and dissemination project for carbohydrate and glycoconjugate related data.
ARCHS4
Thumbnail image for ARCHS4
ARCHS4 provides access to gene-function predictions based on RNA-seq co-expression, and gene expression levels across cell and tissues.
Approved Drugs (0)
No approved drugs found
Active Ligands (0)
No active ligands found
Protein-Protein Interactions (30)
SLC4A1AP
Tdark
Family:  Transporter
Novelty:  0.41125302
p_int:  0.999978062
p_ni:  0.000021938
Score:  0.269
Data Source:  BioPlex,STRINGDB
ZCCHC8
Tbio
Novelty:  0.14887134
p_int:  0.998068399
p_ni:  0.001931601
Score:  0.856
Data Source:  BioPlex,STRINGDB
RBM25
Tbio
Novelty:  0.05557892
Score:  0.728
Data Source:  STRINGDB
PCBP3
Tbio
Novelty:  0.11681812
Score:  0.72
Data Source:  STRINGDB
RBM17
Tbio
Novelty:  0.04840999
Score:  0.717
Data Source:  STRINGDB
SCAF4
Tbio
Novelty:  0.08174395
Score:  0.664
Data Source:  STRINGDB
RBM15
Tbio
Novelty:  0.00948292
Score:  0.635
Data Source:  STRINGDB
LIPI
Tbio
Family:  Enzyme
Novelty:  0.00512911
Score:  0.606
Data Source:  STRINGDB
RBM19
Tbio
Novelty:  0.15784228
Score:  0.605
Data Source:  STRINGDB
NOVA1
Tbio
Novelty:  0.01298544
Score:  0.601
Data Source:  STRINGDB
Nearest Tclin Targets
Nearest Tclin calculations are only available for targets with KEGG Pathway annotations.
Pathways (0)
No pathways found
Viral Interactions (0)
No viral interactions found
Disease Associations (null)
No disease associations found
GWAS Traits (0)
No GWAS traits found
IDG Resources
No IDG generated resources found
Orthologs (10)
1 – 5 of 10
Species
Name
Source ID
Gene ID
OMA
EggNOG
Inparanoid
Chimp
RNA binding motif protein 11
VGNC:1130
473914
Macaque
RNA binding motif protein 11
694455
Mouse
MGI:2447622
224344
Rat
RGD:1305195
288321
Dog
RNA binding motif protein 11
VGNC:45405
478383
Species
Name
OMA
EggNOG
Inparanoid
Chimp
RNA binding motif protein 11
Macaque
RNA binding motif protein 11
Mouse
Rat
Dog
RNA binding motif protein 11
Publication Statistics
PubMed Score 4.62
PubMed score by year
PubTator Score 1.08
PubTator score by year
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Related Publications
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PMID
Year
Title