RBM10
RNA-binding protein 10
Protein Summary
May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins (PubMed:28431233). This gene encodes a nuclear protein that belongs to a family proteins that contain an RNA-binding motif. The encoded protein associates with hnRNP proteins and may be involved in regulating alternative splicing. Defects in this gene are the cause of the X-linked recessive disorder, TARP syndrome. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Mar 2011]
- ENST00000329236
- ENSP00000328848
- ENSG00000182872
- ENST00000345781
- ENSP00000329659
- ENST00000377604
- ENSP00000366829
- ENST00000628161
- ENSP00000486115
- DXS8237E
- GPATC9
- GPATCH9
- KIAA0122
- S1-1
- TARPS
- GPATC9
- ZRANB5
- GPATCH9
- DXS8237E
Most Knowledge About | Knowledge Value
(0 to 1 scale) | ||
|---|---|---|---|
interacting protein | 1 | ||
histone modification site profile | 0.91 | ||
protein complex | 0.88 | ||
protein domain | 0.85 | ||
ligand (protein) perturbation | 0.83 | ||
Protein Classes
IDG Development Level Summary
These are targets about which virtually nothing is known. They do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 64.07 (req: < 5)
Gene RIFs: 45 (req: <= 3)
Antibodies: 182 (req: <= 50)
These targets do not have known drug or small molecule activities
- AND - satisfy two or more of the following criteria:
Pubmed score: 64.07 (req: >= 5)
Gene RIFs: 45 (req: > 3)
Antibodies: 182 (req: > 50)
- OR - satisfy the following criterion:
Gene Ontology Terms: 13
Target has at least one ChEMBL compound with an activity cutoff of < 30 nM - AND - satisfies the preceding conditions
Active Ligand: 0
Target has at least one approved drug - AND - satisfies the preceding conditions
Active Drug: 0